How to Apply

When an opportunity in which you are interested becomes available, please submit your resume and cover letter with job code and salary requirements to the address below. All submissions will be evaluated. Interviews will be conducted for those applicants who most strongly fit our needs. If you are not contacted for an interview, your resume will remain on file and active for one year.


E-mail

All e-mails should include the specific job code in the subject line, resumes should be attached as PDF’s and sent to careers@deciphera.com.
No phone calls please.


Open Positions

Associate Director, Clinical Supply Operations

Job #: :02-267

Job Title: Associate Director, Clinical Supply Operations

Location: Waltham, MA

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking an Associate Director of Clinical Supply Operations to manage day to day clinical supply activities and logistics within the Clinical Operations Group as further described below. This position will design, develop, and implement the clinical supplies strategy to ensure appropriate processes are established, and in order to achieve clinical supplies for key deliverables for each study within the program. This position will also manage supply chain activities for Phase I through commercialization and assist in the development and implementation of Investigational Supply Operations processes and procedures.

This position will report to the VP of Clinical Operations and be located in the Waltham, MA office.

Key Responsibilities:
• Plans, establishes, manages and monitors forecast activities related to drug product, and clinical supplies for multiple programs and study level, based on clinical study protocol and clinical development plans.
• Responsible for all levels of studies, ranging from simple and complex, requiring in-depth understanding of GMPs, project management, IXRS, medication management and/or use of advanced simulation tools.
• Independently responsible for development, and implementation of clinical supply plans, based on clinical development plans.
• Responsible for scheduling and delivery of CTM including strategies for creating label and packaging design, randomization, packaging, labelling and distribution of clinical supplies.
• Manages external consultants and third party vendors, including collaboration with QA on vendor selection and quality and supplier agreement development, to ensure timely and quality delivery of CTM that meets study protocol, regulatory, and budgetary requirements.
• Ensures that key project milestones are met, negotiates and communicates supply plan timelines to internal and external customers and partners.
• Develops and manages the forecasting and ordering investigational product, commercial and comparator material in global trials and share best practices with global/local sourcing teams as appropriate.
• Independently creates clinical supply study budgets.
• Monitors spend to-date compared to the approved study budget.
• Accountable and responsible for amending budgets through defined change management processes.
• Manages all finance activities with clinical team and clinical finance including request for proposal for bidding and vendor selection, purchase orders and invoice approval.
• Ensures uninterrupted supplies throughout the duration of a clinical study program.
• Maintains/tracks inventory of available clinical supplies and tracks expiration dates.
• Coordinates with CMC, in-licensing and QA partners to manage technical and quality issues to facilitate uninterrupted supplies.
• Proactively drives cross-functional activities.
• Works with other line functions and external partners to manage complex projects.
• Identifies potential system/technology improvements/enhancements.
• Maintains and ensures compliance to all SOPs.
• Identifies gaps and makes appropriate mitigation recommendations to ensure global compliance.
• Develops new functional SOPs, Policies/Plans as necessary.

• Provides training to staff.

Required Qualifications:
• 7 + years’ experience in the biopharmaceutical industry supporting complex global trials
• Ability to effectively prioritize and manage multiple projects and tasks.
• Possess a flexible approach to problem solving and strong negotiations skills.
• A team player, who listens effectively and invites response and discussion.

• A collaborator who communicates in an open, clear, complete, timely and consistent manner.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Associate Director/Director, Drug Product Manufacturing Science & Technology (MS&T)

Job #::02-268

Job Title: Associate Director/Director, Drug Product Manufacturing Science & Technology (MS&T)

Location: Waltham, MA

Role Summary:

Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

We are seeking an Associate Director/Director, Drug Product Manufacturing Science and Technology (MS&T), who will have responsibility for leading and managing late-stage development, validation and commercial manufacturing activities for drug product and packaging. The scope of the role encompasses late stage process development, scale-up, Process Performance Qualification (PPQ), routine commercial manufacturing, technical transfer and Continued Process Verification. Operating within a virtual (100% outsourced) business model, the incumbent will have accountability for CDMO oversight, and the development of strong and enduring business partnerships. The successful candidate will also assume a key role in the development, review and approval of Module 3 sections of CTD regulatory submissions, pre-approval inspections (PAIs) and written responses to regulatory authorities.

The successful candidate will have significant experience in CMC development and commercialization of small molecules and an in-depth understanding of critical-path activities and interdisciplinary connections associated with validation and commercial launch. S/he will possess strong leadership, management and communication skills, ensuring that external business partners understand and respect program goals, objectives, priorities, and timelines.

This position will report to the Sr. Director, MS&T and be located in the Waltham, MA office.

Key Responsibilities:

• Lead and manage cross-functional teams engaged in external cGMP manufacturing of bulk drug product and finished goods.
• Lead and manage process transfers, associated site implementation and PPQ to support supply chain expansion activities and post-approval continuous improvement initiatives.
• Monitor, track and trend process performance. Develop and implement data analytics to support investigations and provide historical baseline for future operational and process-related improvements.
• Support investigations, root cause identification and CAPA implementation associated with manufacturing deviations and associated quality events.
• Work closely with internal Quality Assurance, Regulatory CMC, Supply Chain and Commercial functions and external manufacturing operations to ensure operational excellence with respect to timelines, budgets, and attainment of technical, regulatory and business goals/milestones.
• Play a key role in the selection of drug product CDMOs based upon core capabilities, capacity and track record of regulatory compliance; establish KPIs to monitor site technical, quality and business performance.
• Develop and maintain strong relationships with CDMO business partners.
• Review/approve technical reports, controlled GMP documents and CMC content for Module 3 CTDs.
• Potentially represent the Technical Operations organization in meetings with FDA, EMA and related regulatory authorities.

Required Qualifications:
• A B.S./M.S. degree in chemical engineering, pharmaceutics, chemistry, or related life sciences discipline with at least 10 years of hands-on experience in small-molecule pharmaceutical product development and commercialization.
• Track record of success in leading and managing small-molecule drug product MS&T program through validation in a 100% outsourced environment.
• Thorough knowledge of current global regulatory expectations and industry best practice for Process Performance Qualification , Continued Process Verifications and implementation of Quality by design (QbD) principles.
• Strong vendor/supplier management skills and excellent communication and cross-functional collaboration skills.
• Competency in developing, implementing and delivering CMC project plans (milestones, timelines, resources, etc.) to successful endpoints.
• Ability to articulate complex issues and ideas with clarity to enable understanding and decision making.
• Ability to work successfully in a team/matrix environment and independently, as required.
• Ability to influence cross-functionally to enable improvements and enhance performance across CMC development, MS&T and supply chain functions.
• Pragmatic, solution-oriented thinker who possesses a “can do” and ”whatever it takes” attitude, coupled with excellent organizational and communication skills.
• Strong interpersonal skills with the ability to influence others, negotiate during situational conflict, and establish the best forward path in the face of competing points of view.
• Ability to travel (20%) to CDMO domestic and international sites.
• Fluency with standard computer software packages (MS Word, Excel, PowerPoint, and Project) and JMP (or similar statistical tools). 

Preferred Qualifications:
• Experience in developing and commercializing drugs for oncology and/or orphan diseases is strongly preferred.
• A Ph.D. degree in an engineering or life sciences discipline or M.B.A. in operations management is highly desired.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Senior Scientist, Translational Medicine

Job #: :02-266

Job Title: Senior Scientist, Translational Medicine

Location: Waltham, MA

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking a Sr. Scientist, Translational Medicine who will report to the Director, Translational Medicine and will be part of the clinical development team in Waltham, MA. The successful candidate will grow into a lead scientist role responsible for developing, implementing and executing translational research strategy to support clinical programs in multiple oncology diseases. This individual will also have opportunities to be the translational medicine representative on development teams and assume primary translational responsibility such as implementing biomarker studies and analyzing patient data.

Key Responsibilities:
• Design biomarker clinical studies to test novel hypothesis on drug MOA, identify tumor microenvironment/tumor related biomarkers and patient population susceptible to respond to novel agents in oncology.
• Implements translational activities through direct interaction with clinical research physicians, statistician, clinical and translational operation, CRO and academic experts and internal translational medicine scientists.
• Analyze biomarker for company sponsored clinical studies through working with internal relevant functions and CRO.
• Responsible for evaluating CRO for assay and analytical capabilities, creating contracts, interact with CRO for execution of scientific services.
• Responsible for authoring study reports, biomarker components of clinical trial related documents including IB, IND, CSR, as well as regulatory submission.

Required Qualifications:
• A Ph.D or M.D. Ph.D in life science disciplines or medical sciences with at least 5 years of in biotechnology or pharmaceutical industry experience.
• Candidate must be a rigorous and detail-oriented scientist. Process strong scientific background and solid understanding of oncology.
• Knowledge of clinical biomarker discovery, development and analysis, including drug MOA, assay development/validation and cutting-edge scientific platform.
• Must be results and detail oriented, independent and self-driven.
• Must commit to help the team achieve deliverables and meet aggressive timelines.
• Recognize cross functional issues and provide expert guidance to multi-disciplinary team and Sr. management. Has a track record of delivering results, driving continuous improvements and building effective cross-functional networks.
• Strong verbal and written communication skills and excellent organizational skills

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Director, Advanced Analytics & Data Management

Job #: :03-226

Reports to: Vice President, Commercial Insights & Operations

Location: Waltham, MA

Position Summary:
Deciphera Pharmaceuticals is searching for a highly motivated, insightful, and resourceful individual to join the newly formed Commercial Insights and Operations team.

Reporting directly to the Vice President of Commercial Insights and Analytics, this highly visible role will have the rare opportunity to build the Advanced Analytics and Data Management function form the ground up as we prepare to launch Deciphera’s first commercial therapy.

This role will be responsible for leading the design, development, implementation, and maintenance of Deciphera’s commercial data environment (CDE). To include data strategy, sourcing, integration, and management; data infrastructure design and implementation; analytics and reporting needs assessment and development; key vendor partner identification and integration; etc. The CDE will become the “nerve center” for the commercial organization and support key needs of the company more broadly. It must therefore thoughtfully and powerfully address a variety of needs of multiple functions across the organization while maintaining a high priority on ease of use and cost-efficiency.

Company Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality and durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.
We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:
• Providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• Surrounded by diverse, multi-disciplinary, dedicated and talented workforce who are passionate about achieving excellence in all they do
• Driven by a work environment that allows employees to balance their priorities
• And above all else, focused on doing the right thing for the patients and their caregivers

Our Drug Discovery Engine – Kinase Switch Control Platform
Our proprietary drug discovery platform is based on our deep insight into the biology of kinases, which are regulated by control of their shape, or conformation. The transformation of a kinase from an inactive to an activated state is dependent upon the interaction of one region of the kinase called the activation switch with an area called the switch pocket; a mechanism of activation that is common among all kinases. While this activation mechanism is common among kinases, the molecular structure of the activation switch and the switch pocket varies. At Deciphera, we take advantage of this activation mechanism by engineering inhibitors that selectively bind the switch pocket, preventing activation of the kinase. By directly targeting the switch pocket, we can engineer novel kinase inhibitors that are highly selective but also broadly active against the target kinase, covering both wild-type and many or all known mutant or amplified forms.
We believe no other kinase inhibitors on the market or active in clinical development directly target the switch pocket region, making Deciphera the only biopharmaceutical company that is currently developing kinase inhibitors using this approach. Our kinase switch control inhibitors interact at a molecular level in a way that is distinct from other kinase inhibitors and are designed to generate higher and more durable rates of response. Using our kinase switch control inhibitor platform, we have developed a diverse pipeline of differentiated, wholly owned, orally administered drug candidates that include three clinical-stage and two research-stage programs.

Key Responsibilities:
• Build a launch ready CDE and KPI reporting that will earn and keep the trust of the organization regarding the accuracy of our commercial data assets and the insight that it generates
• Develop commercial data management roadmap and overarching data strategy
• Standup cloud-based data management/warehouse environment and manage ongoing operations
• Establish and maintain commercial data governance process and hierarchical customer mastering operation
• Ensure seamless, timely and accurate ingestion, validation/QC, and integration of multiple internal and external data sources (specialty pharmacy, syndicated data, claims-based and/or EMR data, CRM, Oracle, etc) into the CDE
• Select, design and implement custom-built “self-serve” BI platform and big data analytics and predictive analytics solutions using modern approaches and relevant tools (i.e. Tableau, Qlik, Business Objects, Wave/Einstein Analytics, Python, R, etc)
• Partner with other architects/consultant and departments to ensure application components align with a specific stakeholder needs and meet performance goals of corporate systems
• Effectively and seamlessly work at multiple “altitudes” within the organization. Maintains a “no job is too big or too small” attitude necessary to succeed in a startup environment
• Serve as an individual contributor to manage multiple projects at any given time while simultaneously building and leading the function
• Partner across Commercial Insights & Operations to conduct advanced analysis (cohort-based insight generation, ROI/promotion effectiveness modeling, predictive modeling, etc) as needed
• Champion intellectual agility and use of analytics to define long-term strategy and a flexible approach to execution
• Demonstrate managerial courage to make and stand by difficult decisions
• Display high degree of creativity and innovation in problem solving, proactively developing new approaches, processes, and methodologies to maintain consistent and reliable commercial operations
• Expertly manage vendor partners/consultants and leading project teams to achieve milestones and objectives
• Operate in adherence with legal, compliance, and regulatory guidelines in the pharmaceutical industry; build SOPs, guidelines and training to ensure broad understanding and compliance with such

Qualifications:
• BS/BA degree in business or related discipline. Advanced degree in a relevant field preferred
• 8+ years of experience within the pharmaceutical, biotechnology or consulting industries
• Oral oncolytic or rare disease experience, including launch experience, is strongly preferred
• 5+ years of progressive experience in advanced analytics roles, data management, System architecture, reporting and/or data science/systems consulting
• Current and relevant perspective on analytics, BI, cloud-based data environments (e.g. AWS or Azure) and CRM platforms and services
• Deep understanding of how to leverage data science methodologies against structured and unstructured data assets (IMS/Symphony prescription and medical claims, CRM, Specialty Pharmacy, EMR data, etc)
• Knowledge of master data management, data governance, and data management and ETL tools, such as Informatica
• Must be a true team player – authentic, humble, able to build a positive team spirit and lead through the ups and downs of a launch, puts success of team above own interests and support everyone’s efforts to grow and develop
• Excellent interpersonal, oral and written communication skills, including ability to synthesize data and deliver a clear overview of commercial strategy, opportunity and risks for the Executive Team
• Demonstrated ability to adapt to changes in the work environment, manage competing demands and adjust approaches/methods to best fit the situation with maturity and professionalism
• Deep experience with pharmaceutical data (e.g., IQVIA, SHA, Patient Claims, Specialty pharmacy, Hub, EMR, etc.)
• Strong business acumen, critical thinking, along with technical and problem-solving skills
• Thrives in fast-paced, minimally structured environment, able to deal with ambiguity and can act without having the complete picture
• Ability to self-direct projects and work with little supervision
• Ability to travel (up to 20% of time as needed)

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Director, Brand Insights & Forecasting

Job #::03-225

Reports to: Vice President, Commercial Insights & Operations

Location: Waltham, MA

Position Summary:
Deciphera Pharmaceuticals is searching for a highly motivated, insightful, and resourceful individual to join the newly formed Commercial Insights and Operations team.
Reporting directly to the Vice President of Commercial Insights and Operations, this highly visible role will have the rare opportunity to build the Brand Insights & Forecasting function from the ground up as we prepare to launch Deciphera’s first commercial therapy.
The Director of Brand Insights and Forecasting is a commercial insights generalist who is able to balance expert intra-personal skills with strong analytical acumen to translate research findings into actionable insights. The person in this role is accountable for identifying, executing, and presenting market/brand insights to guide strategic decisions that inform the creation of all launch materials and to optimize brand performance over time.
The successful candidate for this role must have in-depth experience with a variety of measurement and research methods, demonstrated strategic planning and project management, data evaluation, market research, customer insight generation and forecast triangulation methodologies. As a senior member of the commercial business, this role will serve as an internal consultant to the brand team and Commercial leaders in the organization to drive innovation and forward-thinking strategies centered on patients and customer-focused solutions.

Company Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality and durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:
• Providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• Surrounded by diverse, multi-disciplinary, dedicated and talented workforce who are passionate about achieving excellence in all they do
• Driven by a work environment that allows employees to balance their priorities
• And above all else, focused on doing the right thing for the patients and their caregivers

Our Drug Discovery Engine – Kinase Switch Control Platform
Our proprietary drug discovery platform is based on our deep insight into the biology of kinases, which are regulated by control of their shape, or conformation. The transformation of a kinase from an inactive to an activated state is dependent upon the interaction of one region of the kinase called the activation switch with an area called the switch pocket; a mechanism of activation that is common among all kinases. While this activation mechanism is common among kinases, the molecular structure of the activation switch and the switch pocket varies. At Deciphera, we take advantage of this activation mechanism by engineering inhibitors that selectively bind the switch pocket, preventing activation of the kinase. By directly targeting the switch pocket, we can engineer novel kinase inhibitors that are highly selective but also broadly active against the target kinase, covering both wild-type and many or all known mutant or amplified forms.
We believe no other kinase inhibitors on the market or active in clinical development directly target the switch pocket region, making Deciphera the only biopharmaceutical company that is currently developing kinase inhibitors using this approach. Our kinase switch control inhibitors interact at a molecular level in a way that is distinct from other kinase inhibitors and are designed to generate higher and more durable rates of response. Using our kinase switch control inhibitor platform, we have developed a diverse pipeline of differentiated, wholly owned, orally administered drug candidates that include three clinical-stage and two research-stage programs.

Key Responsibilities:
• Create and leverage brand insights generated from tailored primary and secondary market research studies to guide brand launch strategy and ensure tactics maximize opportunities and minimize risks
o Design and manage all aspects of primary market research across patient, caregiver, physician and payer customers for Commercial, Medical Affairs and Patient Advocacy
o Develop robust cross-functional competitive intelligence function
o Make data-based recommendations by providing business analyses and analytical support to Sr. Management, particularly in areas where data is difficult to access / unreliable and where a high level of analytical skill is required
o Review/develop market research policies and procedures where needed
o Produce timely, accurate and effective reports integrating findings across studies to address key business questions
• Facilitate the forecasting process in collaboration with Commercial partners, Finance and Supply
o Develop key assumptions through cross-functional conversations backed by your in-depth understanding of the therapeutic area dynamics, key product attributes, drivers and barriers to adoption, and expected effectiveness of internal tactical plans
o Develop and maintain models that are appropriately robust to model assumption ranges and output long range Annual and monthly forecasts and a weekly launch forecast, leveraging a variety of approaches to triangulate on the plan and report on LBE
o Develop and implement statistical methodologies and criteria for utilizing various data (syndicated demand, trade, CRM, etc.) to improve the predictive value of forecast models and other analyses
• Build and facilitate key brand planning/performance management processes in partnership with the Brand lead, Field leadership, Finance and Supply chain to ensure effective and timely communication of actual and expected performance against the forecast: e.g. annual situational analysis, quarterly business reviews, forecast Budget, LBE and S&OP
• Develop and maintain excellent internal cross‐functional relationships with relevant stakeholders to ensure alignment with and appropriate support of corporate and functional goals
o Collaborate within Commercial Operations to ensure data integrity and accuracy in reporting
o Participate as a key thought leader of the business planning team by challenging assumptions and identifying key risks and opportunities
o Negotiate with teammates for appropriate allocation of internal analytic, IT, and operational resources ensure commercial launch readiness and ongoing operations
• Provide Insights and forecasting support for Business development and New Product Planning initiatives as needed
• Potential to build analytics and forecasting team as company grows and/or to support global launches
• Operate in adherence with legal, compliance, and regulatory guidelines in the pharmaceutical industry; build SOPs, guidelines and training to ensure broad understanding and compliance with such

Qualifications:
• BS/BA degree in business or related discipline. Advanced degree in a relevant field preferred
• 8+ years of experience within the pharmaceutical, biotechnology or consulting industries
• Oral oncolytic, rare disease and/or launch experience, is preferred
• 5+ years of progressive experience in commercial analytics, brand forecasting, strategic planning, market research, and/or consulting
• Must be a true team player – authentic, humble, able to build a positive team spirit and lead through the ups and downs of a launch, puts success of team above own interests and support everyone’s efforts to grow and develop
• Effectively and seamlessly work at multiple “altitudes” within the organization. Maintains a “no job is too big or too small” attitude necessary to succeed in a startup environment.
• Excellent interpersonal, oral and written communication skills, including ability to synthesize data and deliver a clear overview of commercial strategy, opportunity and risks for the Executive Team
• Demonstrated ability to adapt to changes in the work environment, manage competing demands and adjust approaches/methods to best fit the situation with maturity and professionalism
• Demonstrate managerial courage to make and stand by difficult decisions
• Hands-on experience and proven creativity and innovation in designing/customizing qualitative and quantitative research methodologies to address specific business needs
• Deep experience with commercial data (e.g. Rx, Patient Claims, Specialty pharmacy, Hub, EMR, etc.)
• Strong business acumen, critical thinking, along with technical and problem-solving skills
• Thrives in fast-paced, minimally structured environment, able to deal with ambiguity and can act without having the complete picture
• Ability to self-direct projects and work with little supervision
• Ability to manage periods of heavy domestic travel (20-40% of time based on market research needs)

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Sr. Director, DCC-2618 (Ripretinib) Marketing

Job #: :03-224

Reports to: VP, Marketing

Location: Waltham, MA

Company Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality and durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:
• Providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• Surrounded by diverse, multi-disciplinary, dedicated and talented workforce who are passionate about achieving excellence in all they do
• Driven by a work environment that allows employees to balance their priorities
• And above all else, focused on doing the right thing for the patients and their caregivers

Our Drug Discovery Engine – Kinase Switch Control Platform
Our proprietary drug discovery platform is based on our deep insight into the biology of kinases, which are regulated by control of their shape, or conformation. The transformation of a kinase from an inactive to an activated state is dependent upon the interaction of one region of the kinase called the activation switch with an area called the switch pocket; a mechanism of activation that is common among all kinases. While this activation mechanism is common among kinases, the molecular structure of the activation switch and the switch pocket varies. At Deciphera, we take advantage of this activation mechanism by engineering inhibitors that selectively bind the switch pocket, preventing activation of the kinase. By directly targeting the switch pocket, we can engineer novel kinase inhibitors that are highly selective but also broadly active against the target kinase, covering both wild-type and many or all known mutant or amplified forms.
We believe no other kinase inhibitors on the market or active in clinical development directly target the switch pocket region, making Deciphera the only biopharmaceutical company that is currently developing kinase inhibitors using this approach. Our kinase switch control inhibitors interact at a molecular level in a way that is distinct from other kinase inhibitors and are designed to generate higher and more durable rates of response. Using our kinase switch control inhibitor platform, we have developed a diverse pipeline of differentiated, wholly owned, orally administered drug candidates that include three clinical-stage and two research-stage programs.

Position Summary:
Deciphera is seeking a seasoned, dynamic commercial executive with extensive oncology experience to build and lead the company’s lead asset, DCC 2618 or ripretinib. Reporting to the VP of Marketing, this position will lead Deciphera’s brand strategy and execution for ripretinib, a broad-spectrum KIT and PDGFRa kinase switch control inhibitor currently in development for the treatment of GIST, systemic mastocytosis, and other solid tumors. This is a critical senior leadership role that will be instrumental in Deciphera’s evolution from the clinical stage into a fully-integrated, commercial-stage biopharma company.

Responsibilities:
• Being a product champion – be the strategic lead for ripretinib, and should be able to motivate and excite the entire commercial team (Sales, Market Access, Digital Marketing, Market Research and Analytics) and the company to help drive success of the product
• Being a launch champion –oversee a successful pre-launch and launch planning of ripretinib in GIST indication(s) working closely with cross-functional partners
• Develop comprehensive strategic brand plan for ripretinib with cross functional assistance and work with his/her team to execute on marketing strategies and tactics to support product’s P&L to ensure short term and long term success of the brand
• Plan and oversee the development of advertising and promotional materials and activities including print, online, and other personal and non-personal promotional efforts
• Develop and manage the marketing operating budget and recommend product positioning, messaging and pricing strategy to produce the highest possible long term market share and success for ripretinib
• Identify Market Research and insight needs for ripretinib and work with Market Insights to implement appropriate studies
• Analyze customer insights, monitor brand performance and competitive dynamics to inform/adjust marketing/brand strategy and address customer needs
• Monitor and measure the success of personal and non-personal promotion and recommend modifications/adjustments as appropriate to ensure highest ROIs
• Evaluate new market segments and competitive landscape to identify and recommend emerging opportunities
• Work closely with Sales/Sales Training to ensure promotional messaging implementation and a highly actionable national sales meeting/POA meeting execution
• Collaborate with Medical Affairs and provide input on studies, publications and in the identification and engagement of KOLs (primarily at Institutional and Community level)
• Align with Market Access colleagues to develop impactful/actionable market access/payer strategy and tactics
• Be comfortable in interfacing with/presenting to senior leadership to update them on product performance and other critical information
• Oversee two direct reports to ensure commercial success for ripretinib and provide coaching/mentoring to develop talent pool for the company
• Be the change agent that will help build and maintain the culture as Deciphera transitions from a development stage company to a successful commercial company
• Role involves significant travel (approximately 30% of time) to medical meetings, sales meetings, market research, etc.

Qualifications:
• Proactive, results oriented, self-starter motivated by the desire to do the right thing for the patients and their caregivers
• Bachelor’s degree in a business-related and/or life sciences field required from an accredited school. An MBA or advanced degree preferred but not necessary
• 10+ years of Marketing and related experience in the pharmaceutical industry
• Extensive knowledge of medical, regulatory, legal review process
• Oncology/Launch experience is a must
• Comfortable working in a fast paced, constantly evolving start-up environment
• Excellent people management skills – not only with direct reports but also with cross functional partners and broader organization and outside agencies
• Demonstrated ability to multi-task, show attention to detail and follow-through to completion
• Strong team player and a change agent who further reinforces/enhances Deciphera’s cultural values
• Bring high level of innovation and creativity
• Demonstrated analytical and problem-solving skills
• Excellent written and verbal communication skills
• Demonstrated track record of commercial success in positions with progressive responsibilities
• Must be a true team player – authentic, humble, able to build a positive team spirit and lead through the ups and downs of drug development, puts success of team above own interests and support everyone’s efforts to grow and develop
• Ability and willingness to work effectively and seamlessly at multiple “altitudes” within the organization. Maintains a “no job is too big or too small” attitude necessary to succeed in a startup environment
• Must adhere to Deciphera’s core values, policies, procedures and business ethics

This is a wonderful opportunity to join Deciphera’s select team in a leadership position and become part of an emerging success story that is driven by the company’s unwavering commitment to patients and to its employees. Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Director, Patient Access and Reimbursement Support

Job #::03-223

Reports to: Vice President, Market Access

Location: Waltham, MA

Company Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality and durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:
• Providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• Surrounded by diverse, multi-disciplinary, dedicated and talented workforce who are passionate about achieving excellence in all they do
• Driven by a work environment that allows employees to balance their priorities
• And above all else, focused on doing the right thing for the patients and their caregivers

Our Drug Discovery Engine – Kinase Switch Control Platform
Our proprietary drug discovery platform is based on our deep insight into the biology of kinases, which are regulated by control of their shape, or conformation. The transformation of a kinase from an inactive to an activated state is dependent upon the interaction of one region of the kinase called the activation switch with an area called the switch pocket; a mechanism of activation that is common among all kinases. While this activation mechanism is common among kinases, the molecular structure of the activation switch and the switch pocket varies. At Deciphera, we take advantage of this activation mechanism by engineering inhibitors that selectively bind the switch pocket, preventing activation of the kinase. By directly targeting the switch pocket, we can engineer novel kinase inhibitors that are highly selective but also broadly active against the target kinase, covering both wild-type and many or all known mutant or amplified forms.
We believe no other kinase inhibitors on the market or active in clinical development directly target the switch pocket region, making Deciphera the only biopharmaceutical company that is currently developing kinase inhibitors using this approach. Our kinase switch control inhibitors interact at a molecular level in a way that is distinct from other kinase inhibitors and are designed to generate higher and more durable rates of response. Using our kinase switch control inhibitor platform, we have developed a diverse pipeline of differentiated, wholly owned, orally administered drug candidates that include three clinical-stage and two research-stage programs.

Position Summary:
The Director, Patient Access and Reimbursement Support (Hub) is a newly-created role within Deciphera’s Commercial organization. This role reports to the Vice President of Market Access and it will have a tremendous impact in bringing Deciphera’s first oral cancer therapy to market for patients with gastrointestinal stromal tumors (GIST).
The Director, Patient Access and Reimbursement Support will lead development and execution of the U.S. patient services strategies with the objective of developing and implementing a robust Patient Support Services program for all products in Deciphera’s portfolio. The Director will assess and adapt the services and strategy continuously to ensure that patients have timely and affordable access to their therapies their patient journey.
The successful candidate will have a demonstrable commitment to working for patient-focused pharmaceutical companies and understand the needs for engagement with the cancer or rare disease communities in a compliant manner.

Responsibilities:
• Develop patient service strategies that maximize patient access to therapies; design and build out of all offerings with outside hub vendor and other providers.
• Set strategy, choose hub partner, and build out best in class services for Deciphera patients.
• Provide leadership oversight and management for the effective functioning of the hub by establishing and monitoring program goals and key performance indicators.
• Ensure hub performance is communicated to key stakeholders by developing and implementing performance dashboard and improvement plans as needed.
• Asses, plans, and executes strategies addressing patient-level barriers to product access
• Lead innovation and drive program enhancements that will optimize customer service and patient access to therapies by identifying emerging opportunities.
• Bring an analytic rigor to the patient services discipline and assist the commercial business make data driven decisions.
• Work with specific disease related, national, and global patient organizations to understand needs and communicate Deciphera solutions.
• Travel as necessary with Field Sales, Marketing, Managed Markets to visit accounts/make presentations about company’s reimbursement strategy and services; attend commercial and other relevant business-related meetings
• Build and develop productive working relationships with external service providers and internal cross-functional stakeholders, such as data aggregators, specialty pharmacies and internal commercial operations and legal teams.
• Ensure effective and compliant implementation of Patient Financial Assistance programs.
• Serve as the main triage point with SPP/HUB and field access team to ensure that each patient is appropriately supported through the reimbursement process.
• Provide subject matter expertise and guidance to the development of overall Commercial strategies.
• Partner with Deciphera’s Legal Team ensure compliance to applicable laws and regulations.

Qualifications:
• Proactive, results oriented, self-starter motivated by the desire to do the right thing for the patients and their caregivers
• 10+ years of working in the pharma/biotech space, with at least 5+ years working in market access.
• Understanding of the oncology market place and the specific access support needs for patients with rare diseases.
• Demonstrated ability to build organizational capability and deep experience developing and managing manufacturer hub operations or specialty drug patient services/call center.
• In depth knowledge of pharmaceutical manufacturer compliance, patient confidentiality, product reimbursement and product access requirements.
• Knowledge of US payer coverage and reimbursement environment, CMS policies pertaining to access services as a result of the Affordable Care Act, and pharmaceutical channel dynamics.
• Knowledge of regulations and laws governing the protection of patient identifying information.
• Relevant strategic planning and execution skills including operations management, project/budget management, and working collaboratively with cross functional internal partners and external service partners.
• Proven track record developing and delivering patient access and continuity of care services in a high impact and cost-effective way.
• Must be a true team player – authentic, humble, able to build a positive team spirit and lead through the ups and downs of drug development, puts success of team above own interests and support everyone’s efforts to grow and develop
• Ability and willingness to work effectively and seamlessly at multiple “altitudes” within the organization. Maintains a “no job is too big or too small” attitude necessary to succeed in a startup environment
• Must adhere to Deciphera’s core values, policies, procedures and business ethics

This is a wonderful opportunity to join Deciphera’s select team in a leadership position and become part of an emerging success story that is driven by the company’s unwavering commitment to patients and to its employees. Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Director, Market Access Strategy and Marketing

Job #: :03-222

Reports to: Vice President, Market Access

Location: Waltham, MA

Company Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality and durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:
• Providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• Surrounded by diverse, multi-disciplinary, dedicated and talented workforce who are passionate about achieving excellence in all they do
• Driven by a work environment that allows employees to balance their priorities
• And above all else, focused on doing the right thing for the patients and their caregivers

Our Drug Discovery Engine – Kinase Switch Control Platform
Our proprietary drug discovery platform is based on our deep insight into the biology of kinases, which are regulated by control of their shape, or conformation. The transformation of a kinase from an inactive to an activated state is dependent upon the interaction of one region of the kinase called the activation switch with an area called the switch pocket; a mechanism of activation that is common among all kinases. While this activation mechanism is common among kinases, the molecular structure of the activation switch and the switch pocket varies. At Deciphera, we take advantage of this activation mechanism by engineering inhibitors that selectively bind the switch pocket, preventing activation of the kinase. By directly targeting the switch pocket, we can engineer novel kinase inhibitors that are highly selective but also broadly active against the target kinase, covering both wild-type and many or all known mutant or amplified forms.
We believe no other kinase inhibitors on the market or active in clinical development directly target the switch pocket region, making Deciphera the only biopharmaceutical company that is currently developing kinase inhibitors using this approach. Our kinase switch control inhibitors interact at a molecular level in a way that is distinct from other kinase inhibitors and are designed to generate higher and more durable rates of response. Using our kinase switch control inhibitor platform, we have developed a diverse pipeline of differentiated, wholly owned, orally administered drug candidates that include three clinical-stage and two research-stage programs.

Position Summary:
The Director, Market Access Strategy and Marketing is a newly-created role within Deciphera’s Commercial organization. This role reports to the Vice President of Market Access and it will have a tremendous impact in bringing Deciphera’s first oral cancer therapy to market for patients with gastrointestinal stromal tumors (GIST).
The Director, Market Access Strategy and Marketing will lead development of a comprehensive reimbursement, pricing, health economic value and access strategy to ensure success of the company’s oral oncology therapies. The Director will focus at all times on how to reduce real and perceived barriers to access and ensure that patients receive the Deciphera therapies they have been prescribed. He/she will be responsible for working closely with internal stakeholders to include but not limited to finance, legal, accounting, operations, payer field team, patient support services and HEOR.

Responsibilities:
Access Strategy
• Develop cross functional market access strategies that tie together all aspects of reimbursement, pricing, health economic/value and commercial distribution of the company’s therapies.
• Apply deep understanding of national and local reimbursement trends, policies, guidelines, and evolving health care delivery models to develop access strategies with commercial and government payers, IDNs, and other account segments such as OCM providers.
• Monitor state and federal policy and market reimbursement trends to ensure Deciphera’s access strategies evolve appropriately, are innovative and compliant.
• Understand and communicate how changes in the reimbursement and policy environment can impact Deciphera’s development plans, sales execution, financial forecasting, and corporate messaging.
• Be a key partner to the Deciphera legal team to ensure that risk profile of access programs is understood.
• Lead innovation in the access and reimbursement space for Deciphera’s therapy’s; bring new ideas forward that will enhance the company’s reputation with payers, patients, and providers as a partner in the access space.
• Be the internal expert in access policies issues and work with relevant internal stakeholders to understand the implications; be prepared to advocate how to engage the environment to successful improve patients access to therapy.
Access Marketing
• Lead development of US value messages to communicate the story of Deciphera’s therapy’s to payers, healthcare providers, patients and other decision-makers.
• Develop marketing materials for field-based reimbursement teams to improve customer and patient access and help payers recognize the economic burden of disease in GIST and the value of Deciphera therapy’s and solutions.
• Create support materials for patients and providers outlining hub and other patient support offerings and channel options; development of materials across all channels; personal and non-personal, web and print.
• Develop access marketing materials to support pull-through of coverage with field sales teams.
• Identify the need for, and drive the selection of, external agency partners. Manage agency partners for creation of access materials and affordability solutions for on-time delivery within scope/budget.
• Be the content expert working in partnership with the head of training and development to broaden the understanding of access challenges and opportunities to the broader internal stakeholders.
• Lead development of external access and pricing messaging to non-customer stakeholders like investors, media, and government agencies.
General
• Determine best approach to National organizations (e.g. ACCC, COA, NCODA), payer organizations (AMCP, PCMA, etc.) and state societies (e.g. FLASCO and MSHO) and lead efforts to partner with these organizations.
• Build effective working relationships with key external advisors in partnership with Medical Affairs and patient organizations in partnership with the Head of Patient Advocacy.
• Partner closely with the Director of Patient Support Services, to ensure patient needs are understood and there is alignment of affordability programs with access strategies.
• Partner with Deciphera’s Legal Team ensure compliance to applicable laws and regulations.

Qualifications:
• Proactive, results oriented, self-starter motivated by the desire to do the right thing for the patients and their caregivers
• 10+ years of working in the pharma/biotech space, with at least 5+ years working in market access.
• In-depth knowledge of managed care and impact on therapy access as with external partners and vendors.
• Strong oral and written presentation skills and executive presence.
• Oncology and/or Rare disease experience desired.
• Ability to work in a fast-paced, highly visible and dynamic environment is critical; able to work effectively with ambiguity and incomplete information.
• Ability to influence and lead across functions; operate in a matrix environment.
• Must be a true team player – authentic, humble, able to build a positive team spirit and lead through the ups and downs of drug development, puts success of team above own interests and support everyone’s efforts to grow and develop
• Ability and willingness to work effectively and seamlessly at multiple “altitudes” within the organization. Maintains a “no job is too big or too small” attitude necessary to succeed in a startup environment
• Must adhere to Deciphera’s core values, policies, procedures and business ethics

This is a wonderful opportunity to join Deciphera’s select team in a leadership position and become part of an emerging success story that is driven by the company’s unwavering commitment to patients and to its employees. Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Director, Distribution and Channel Strategy

Job #: :03-221

Reports to: Vice President, Market Access

Location: Waltham, MA

Company Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality and durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:
• Providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• Surrounded by diverse, multi-disciplinary, dedicated and talented workforce who are passionate about achieving excellence in all they do
• Driven by a work environment that allows employees to balance their priorities
• And above all else, focused on doing the right thing for the patients and their caregivers

Our Drug Discovery Engine – Kinase Switch Control Platform
Our proprietary drug discovery platform is based on our deep insight into the biology of kinases, which are regulated by control of their shape, or conformation. The transformation of a kinase from an inactive to an activated state is dependent upon the interaction of one region of the kinase called the activation switch with an area called the switch pocket; a mechanism of activation that is common among all kinases. While this activation mechanism is common among kinases, the molecular structure of the activation switch and the switch pocket varies. At Deciphera, we take advantage of this activation mechanism by engineering inhibitors that selectively bind the switch pocket, preventing activation of the kinase. By directly targeting the switch pocket, we can engineer novel kinase inhibitors that are highly selective but also broadly active against the target kinase, covering both wild-type and many or all known mutant or amplified forms.
We believe no other kinase inhibitors on the market or active in clinical development directly target the switch pocket region, making Deciphera the only biopharmaceutical company that is currently developing kinase inhibitors using this approach. Our kinase switch control inhibitors interact at a molecular level in a way that is distinct from other kinase inhibitors and are designed to generate higher and more durable rates of response. Using our kinase switch control inhibitor platform, we have developed a diverse pipeline of differentiated, wholly owned, orally administered drug candidates that include three clinical-stage and two research-stage programs.

Position Summary:
The Director, Distribution Strategy and Channel Management is a newly-created role within Deciphera’s Commercial organization. This role reports to the Vice President of Market Access and it will have a tremendous impact in bringing Deciphera’s first oral cancer therapy to market for patients with gastrointestinal stromal tumors (GIST).
The Director, Distribution Strategy and Channel Management is responsible for the development and execution of Deciphera’s channel and distribution strategy. He/she will be responsible for negotiating, managing, and implementing all distribution contracts and fee for service agreements within the channel. He/she will be responsible for working closely with internal stakeholders including but not limited to finance, legal, accounting, operations, access field team, and marketing.

Responsibilities:
• Create the launch distribution model for DCC-2618. Identify all possible distribution options, weigh costs, benefits and challenges, and present recommendations. Must consider all aspects from 3PL, specialty distribution, specialty pharmacy, in-office dispensing, etc. and provide a comprehensive and strategic solutions for implementation.
• Define & create business relationships across all contracted and non-contracted wholesale, distributer, and pharmacy accounts.
• Negotiate any contracts for the trade channel ensuring contracts align to commercial goals and lead implementation of agreements once signed.
• Proactively oversee the management of the day-to-day operations of Deciphera’s distribution and channel.
• Direct and implement distribution channel strategy improvements that increase service levels to end customers and patients; analyze program data and market dynamics and recommend programs to improve the overall platform for all customers.
• Bring an analytic rigor to the channel management function; assist the commercial business in making data driven decisions to improve access, sales and the patient experience.
• Manage Order to Delivery cycle activities to ensure contractual requirements (i. e. inventory levels, data delivery and service levels) are met and financial implications are communicated.
• Create weekly process for understanding forecast, demand, and supply needs; partner with supply chain to ensure adequate product is available through channel.
• Prepare and conduct quarterly business reviews with all trade partners in partnership with key internal stakeholders.
• Liaise with field-based teams and internal customers on data and distribution reporting questions to provide answers and resolve inquiries as received including serving as the main point of contact for distribution-related issues
• Incorporates marketplace, industry trends, customers, and competitors to develop a clear vision for channel segment.
• Evaluate competitive activity and identify key opportunities to seek advantage with the channel strategy.
• Establish key metrics for our channel partners and hold them accountable to service level standards while nurturing strong partnerships.
• Develop and implement channel policies and procedures, such as: orders, returns, replacements, credit/rebill requests, inventory, and chargeback processing.
• Stay abreast of industry standards and FMV rules.
• Partner closely with the Director of Patient Support Services to ensure patient needs are met by current channel design.
• Design and develop data strategies that enable Deciphera to identify trends and opportunities to improve distribution efficiencies and outcomes.
• Partner with Deciphera’s Legal Team ensure compliance to applicable laws and regulations.

Qualifications:
• Proactive, results oriented, self-starter motivated by the desire to do the right thing for the patients and their caregivers
• Bachelor’s degree required. MBA preferred
• 10+ years of working in the pharma/biotech space, with at least 5+ years working with wholesale/specialty distributors and specialty pharmacies, specifically setting channel strategy and pulling through contracts.
• Experience with oral oncology or rare oral therapy.
• Outstanding relationships with channel partners, pharmacy customers, and service vendors.
• In-depth knowledge of managed care and impact on product access as with external partners and vendors.
• Strong oral and written presentation skills and executive presence.
• Ability to work in a fast-paced, highly visible and dynamic environment is critical; able to work effectively with ambiguity and incomplete information.
• Ability to influence and lead across functions; operate in a matrix environment.
• Must be a true team player – authentic, humble, able to build a positive team spirit and lead through the ups and downs of drug development, puts success of team above own interests and support everyone’s efforts to grow and develop
• Ability and willingness to work effectively and seamlessly at multiple “altitudes” within the organization. Maintains a “no job is too big or too small” attitude necessary to succeed in a startup environment
• Must adhere to Deciphera’s core values, policies, procedures and business ethics

This is a wonderful opportunity to join Deciphera’s select team in a leadership position and become part of an emerging success story that is driven by the company’s unwavering commitment to patients and to its employees. Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

Close
Associate Director/Director, DCC-2618 (Ripretinib) Marketing

Job #: :03-220

Reports to: Sr. Director, Marketing

Location: Waltham, MA

Company Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality and durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:
• Providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• Surrounded by diverse, multi-disciplinary, dedicated and talented workforce who are passionate about achieving excellence in all they do
• Driven by a work environment that allows employees to balance their priorities
• And above all else, focused on doing the right thing for the patients and their caregivers

Our Drug Discovery Engine – Kinase Switch Control Platform
Our proprietary drug discovery platform is based on our deep insight into the biology of kinases, which are regulated by control of their shape, or conformation. The transformation of a kinase from an inactive to an activated state is dependent upon the interaction of one region of the kinase called the activation switch with an area called the switch pocket; a mechanism of activation that is common among all kinases. While this activation mechanism is common among kinases, the molecular structure of the activation switch and the switch pocket varies. At Deciphera, we take advantage of this activation mechanism by engineering inhibitors that selectively bind the switch pocket, preventing activation of the kinase. By directly targeting the switch pocket, we can engineer novel kinase inhibitors that are highly selective but also broadly active against the target kinase, covering both wild-type and many or all known mutant or amplified forms.
We believe no other kinase inhibitors on the market or active in clinical development directly target the switch pocket region, making Deciphera the only biopharmaceutical company that is currently developing kinase inhibitors using this approach. Our kinase switch control inhibitors interact at a molecular level in a way that is distinct from other kinase inhibitors and are designed to generate higher and more durable rates of response. Using our kinase switch control inhibitor platform, we have developed a diverse pipeline of differentiated, wholly owned, orally administered drug candidates that include three clinical-stage and two research-stage programs.

Position Summary:
Deciphera is seeking a seasoned, dynamic commercial executive with extensive oncology experience to help with the launch of the company’s lead asset, DCC 2618 or ripretinib. Reporting to the Senior Director of Marketing, this position will help lead Deciphera’s brand strategy and tactical execution for ripretinib, a broad-spectrum KIT and PDGFRa kinase switch control inhibitor currently in development for the treatment of GIST, systemic mastocytosis, and other solid tumors. This is a critical leadership role that will be instrumental in Deciphera’s evolution from the clinical stage into a fully-integrated, commercial-stage biopharma company.

Responsibilities:
• Being a product champion –Be the promotional lead for ripretinib and should be able to motivate and excite the entire commercial team (Sales, Market Access, Digital Marketing, Market Research and Analytics) and the company to help drive success of the product
• Being a launch champion –oversee a successful pre-launch and launch planning of ripretinib in GIST indication(s) working closely with cross-functional partners
• Help develop comprehensive strategic brand plan for ripretinib with cross functional assistance
• Lead the delivery of the operational plan (including promotional messaging development, assessing innovative and optimal promotional mix, development and implementation of speaker programs, sales training, and management of agency of record) and secure support from colleagues to help achieve goals
• Work closely with the cross functional team to invite broad input in the development and delivery of promotional, educational, and sales campaign materials
• Ensure effective role out of marketing campaigns/messages to the field team through plan of action meetings (POA)
• He/she should aim to spend enough time in the field in order to better understand the customers and achieve a realistic vision of the market
• Closely manage marketing budgets to ensure expenditures are aligned with the brand plan
• Plan and oversee the development of advertising and promotional materials and activities including print, online, and other personal and non-personal promotional efforts in accordance with regulatory requirements
• Identify Market Research and insight needs for ripretinib and work with Market Insights to implement appropriate studies
• Analyze customer insights, monitor brand performance and competitive dynamics to inform/adjust marketing/brand strategy and address customer needs
• Partner with Analytics to implement appropriate KPIs to monitor and measure the success of personal and non-personal promotion and recommend modifications/ adjustments as appropriate to ensure highest ROIs
• Evaluate new market segments and competitive landscape to identify and recommend emerging opportunities
• Collaborate with Medical Affairs in the identification and engagement of KOLs (primarily at Institutional and Community level)
• Align with Market Access colleagues to develop impactful/actionable market access/payer strategy and tactics
• Be comfortable in interfacing with/presenting to senior leadership to update them on product performance and other critical information
• Be the change agent that will help build and maintain the culture as Deciphera transitions from a development stage company to a successful commercial company
• Utilize innovative thinking to overcome barriers and hurdles
• Role involves significant travel (approximately 30% of time) to medical meetings, sales meetings, market research, etc.

Qualifications:
• Proactive, results oriented, self-starter motivated by the desire to do the right thing for the patients and their caregivers
• Bachelor’s degree in a business-related and/or life sciences field required. An MBA or advanced degree preferred
• 5-7 years of Marketing and related experience in the pharmaceutical industry
• Oncology/Launch experience is a must. Knowledge of oral oncolytics is preferred
• Extensive knowledge of medical, regulatory, legal review process
• Comfortable working in a fast paced, constantly evolving start-up environment
• Excellent people management skills – not only with direct reports but also with cross functional partners and broader organization and outside agencies
• Demonstrated ability to multi-task, show attention to detail and follow-through to completion
• Strong team player and a change agent who further reinforces/enhances Deciphera’s cultural values
• Bring high level of innovation and creativity
• Demonstrated analytical and problem-solving skills
• Excellent written and verbal communication skills
• Demonstrated track record of commercial success in positions with progressive responsibilities
• Must be a true team player – authentic, humble, able to build a positive team spirit, puts success of team above own interests
• Ability and willingness to work effectively and seamlessly at multiple “altitudes” within the organization. Maintains a “no job is too big or too small” attitude necessary to succeed in a startup environment.
• Must adhere to Deciphera’s core values, policies, procedures and business ethics

This is a wonderful opportunity to join Deciphera’s select team and become part of an emerging success story that is driven by the company’s unwavering commitment to patients and to its employees. Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Senior Clinical Business Analyst

Job #:02-265

Job Title: Senior Clinical Business Analyst


Location: Waltham, MA
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients by tackling key mechanisms of drug resistance that limit the rate and/or durability of response to existing cancer therapies. Our small molecule drug candidates are directed against an important family of enzymes called kinases, known to be directly involved in the growth and spread of many cancers. We use our deep understanding of kinase biology together with a proprietary chemistry library to purposefully design compounds that maintain kinases in a “switched off’ or inactivated conformation. These therapies comprise tumor-targeted agents designed to address therapeutic resistance causing mutations and immuno-targeted agents designed to control the activation of immune kinases that suppress critical immune system regulators, such as macrophages. We have used our platform to develop a diverse pipeline of tumor-targeted and immuno-targeted drug candidates designed to improve outcomes for patients with cancer by improving the quality, rate and/or durability of their response to treatment.,
This position will report to the Director of Clinical Business Planning and be located in the Waltham office.


Role Summary:

We are seeking a dynamic individual to join our Clinical Operations department to contribute to the success of Deciphera, a high-growth biotech company in Waltham. This position will be an integral member of Clinical Business Operations in support of Global Clinical Site Payment Management. Key responsibilities include ensuring clinical study sites are set up properly for payments as well as overseeing the accurate and timely payments to sites. This position requires strong organizational and analytical skills, resourcefulness, and autonomy in accomplishing a wide variety of tasks. The Senior Clinical Business Analyst will collaborate across the Clinical and Finance organizations and have the opportunity to help impact the lives of our patients.

Primary responsibilities:

Site Payments:

• Provide integral support for site payment vendor management
• Review the accuracy of the site payment configurations as built within the vendor payment system
• Work with Deciphera Clinical Project Managers and/or Clinical Trial Associates for study, site, and patient specific budget/payment inquiries
• Suggest modifications to budget templates and/or parameters based upon ongoing experience with clinical trial activity
• Ensure final CTA, including Schedule of Assessments and Budget Exhibits, are clear to enable payments to be made via site payment vendor
• Review for consistency in content across core documents, i.e., CTA, Budget Exhibit and Excel budget
• Review and approve site payments and other payment activities
• Qc and analytical support for actual expenses as related to site payment activity
• Work with Accounting and Finance organization as needed


Business Planning/Operations:

• Provide support in execution of the quarterly forecast and budget cycles
• Assist in preparation of forecasting meeting minutes
• Clinical Operations and/or Finance activities as needed

Activities May Include:

• Provide assistance with site financial issues as needed
• Contracts support such as assistance with implementation of a Contracts Management System
• Review and approve site budget templates for each study developed by CRO, including country specific modifications
Required Qualifications:
• 3-5 years of clinical trial experience at a clinical site, CRO, or sponsor biopharmaceutical organization
• Prior in-house experience as a member of a clinical operations department in a biotechnology or pharmaceutical company strongly preferred
• BS/BA or equivalent degree
• Strong EXCEL skills
• Strong attention to detail and highly analytical
• Demonstrated ability to multi-task, problem-solve and operate in a fast-paced environment
• Excellent verbal and written communication skills
• Flexibility to adapt to the dynamic needs of a growing biotech company
Preferred Qualifications:
• Small company experience is a plus for this is a hands-on individual contributor role.
• Prior experience working with site payment vendor(s) an incredible plus
• Clinical trial experience specific to Oncology

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for health care and/or dependent care.

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Medical Science Liaison (MSL)

Job #::02-264

Job Title: Medical Science Liaison (MSL)

Location: Remote/Field Based (12 Locations)

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking a Medical Science Liaison (MSL), field-based scientific/clinical experts that will report to a Regional Director of MSLs within the Medical Affairs (MA) department. The MSL is a highly trained professional with strong clinical and/or scientific backgrounds who must have excellent communication skills. The MSL is responsible for identifying, developing and managing relationships with current and future Healthcare Providers(HCP’s) in academic and community practices.
This position is available as a remote position from home and will have significant expectations for travel.

Key Responsibilities:
• Exchange complex medical & scientific information with the oncology community.
• Develop valued and productive scientific relationships with Opinion Leaders (OLs) and other disease experts.
• Provide medical/scientific presentations to internal & external groups.
• Provide internal Medical stakeholders with feedback and insights from interactions and discussions with HCPs.
• Assist with awareness of company-sponsored clinical trials and investigator-initiated trials (ISTs).
• Provide support at professional meetings, including staffing exhibits, collecting competitive intelligence and developing tools that support the function.
• Adhere to corporate and healthcare compliance guidance in all activities, including those related to clinical trials, scientific interactions with internal and external groups, and responses to unsolicited requests for medical/scientific information.
• Maintain clinical, scientific, and technical expertise in specific therapeutic areas; review scientific journals, attend scientific and key technical meetings.
• Represent the company and Medical Affairs during exchanges with the medical/scientific community.
• Establish and maintain ongoing long-term collaborative peer-to-peer relationships with Oncologists, and other HCPs within their assigned territory.
• Respond to and document unsolicited requests for scientific information for Deciphera’s programs and other products, including those in development.
• Engage with assigned Medical Groups to support their scientific and research needs as consistent with Deciphera’s Medical Affairs strategy.
• Collaborate with publication planning to support development of publications and communications.
• Facilitate investigator interactions with Medical Directors and other internal stakeholders.
• Provide clinical input and training to internal functions within regulatory guidelines.
• Provide support for content development and delivery of clinical presentations at Advisory Boards.

Required Qualifications:
• PharmD, PhD or RN with advanced degree preferred.
• 5+ years of experience in oncological malignancies, preferred.
• 5+ years of experience as field-based MSL, preferred.
• 8+ years of experience in industry (e.g., biotech/pharmaceutical/medical device company, Contract Research Organization), academic research, or public health preferred.
• Experience with clinical research, publication activities, congress/conference and presenting scientific data.
• Experience functioning as a field-based employee preferred.
• Training and/or knowledge of Good Clinical Practice (GCP) and global regulations
• Ability to effectively build relationships and work with global KOL’s.
• Think strategically; apply knowledge and analytical skills in a highly regulated environment; and align medical and commercial strategies
• Ability to summarize complex information and present in a clear, concise, and scientifically accurate manner to a range of audiences
• Knowledge of ICH guidelines, FDA Drug Regulations with respect to DDMAC, PhRMA Principles on Conduct of Clinical Trials and Communication of Clinical Trial Results, and OIG Compliance Program Guidance for Pharmaceutical Manufacturers.
• Excellent communication skills
• Strong problem solving, decision-making, influencing, and negotiation skills.
• Able to travel overnight (up to 60%)

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Regional Director, Medical Science Liaison (MSL)

Job #::02-263

Job Title: Regional Director, Medical Science Liaison (MSL)

Location: Remote/Field Based

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking a Regional Director, Medical Science Liaison who will have regional responsibility for building, leading, managing, and supporting the US MSL field team and will report to the National MSL Director. Together with the National MSL Director and VP of Medical Affairs, the Regional Director, MSL will build the team and establish the long‐term vision, strategy, plans, objectives, and infrastructure for the MSL team. The successful candidate will have significant experience facilitating strong MSL relationships with the external scientific and medical community. The Regional Director, MSL will be accountable for regional execution of the medical affairs program strategy and assure Medical Science Liaison activity execution within expected scope, budget and timelines in support of Deciphera’s pipeline agents. The Regional Director, MSL will also maintain a region of coverage for Key Opinion Leader engagement, to provide medical support for the brand plans, to support development strategies and initiatives for Deciphera’s programs and advance the body of scientific knowledge.
This position is available as a remote position from home and will have significant expectations for travel.

Key Responsibilities:
• Build, lead and manage a regional field – based team of scientific professionals in their successful delivery of medical education and support of Investigator Initiated clinical trials in Oncology.
• Identify candidates, hire, train, develop, and manage a team of MSLs to implement field initiatives ensuring the development of best practices and scientifically‐based materials that are compliant with all legal and regulatory and company guidelines.
• In collaboration with key internal stakeholders, lead the development and execution of Deciphera’s external engagement and educational strategies for centers of excellence, HCP’s, and thought leaders.
• Lead medical education through communication of scientific information.

• Ensure high quality presentations of scientific data in various settings, including advisory boards, investigator meetings, to enhance product/disease state knowledge.
• Provide support to clinical operations for investigators in ongoing clinical trials, investigator-initiated research, and registries consistent with company objectives and regulations.
• Lead Deciphera’s medical team at national and regional scientific meetings including staffing medical affairs booths, gathering competitive intelligence, and developing pre and post‐conference scientific materials.
• Identify key deliverables, insights, and metrics that highlight the value of the MSL organization and communicate with senior leadership at Deciphera on an ongoing basis.
• Track and provide quantitative and qualitative data from MSL activities that demonstrate customer impact to the Deciphera organization and ensure goal achievement.

Required Qualifications:
• PharmD, PhD, or MD preferred. Advanced degree Nurses, NPs, PAs, or those with a Master’s degree in life sciences with pharmaceutical industry and clinical research experience are also welcome to apply.
• Exceptional leadership/management skills; prefer 5 years of experience leading field based MSL teams.
• Thorough understanding of applicable federal and state regulatory requirements for field‐based scientific personnel; successful track record of compliance.

• Experience/expertise in interpretation of scientific data, market research, competitive intelligence tools, drug information systems, and developing medical educational strategies.

• Outstanding written and verbal communication/listening and presentation skills.
• Previous success translating/tailoring complex scientific concepts into simple language for targeted audiences.

• Demonstrated problem solving abilities and strong organizational skills.
• History of collaboration/teamwork; reputation for successful partnering with internal and external stakeholders, including medical opinion leaders, large group practices, medical directors and MCO professionals.

• Good understanding of clinical development and commercial environment.
• Ability to work successfully in a team/matrix environment and independently, as required.
• Pragmatic, solution-oriented thinker who possesses a “can do” and” whatever it takes” attitude, coupled with excellent organizational and communication skills.

• Strong interpersonal skills with the ability to motivate and influence others, negotiate during situational conflict, and establish the best forward path in the face of competing points of view.
• Proficiency with Veeva and Microsoft Office; in depth Word, PowerPoint & Excel skills.
• Ability to travel (60%).

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Medical Director, GIST

Job #::02-262

Job Title: Medical Director, GIST

Location: Waltham, MA

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking a Medical Director for our Medical Affairs team in the Home office. The Medical Director plays a pivotal role and provides clinical expertise to the GIST therapeutic area and will work closely with a cross functional team. This position will report directly into the Vice President, Medical Affairs.

Key Responsibilities:
• Leading GIST Medical Affairs activities in the pipeline.
• Developing and executing a highly efficient, integrated global medical affairs/scientific strategy, including scientific evidence generation.
• Providing relevant data evidence to ensure that the strategy is clearly defined and consistent with clinical development and commercial strategic objectives and activities for selected products and initiatives.
• Reviewing and approving medical and scientific content of Regulatory, Safety, Scientific Affairs, Medical Affairs, and Commercial.
• Ensuring that all data on GIST programs generated by the company or investigator sponsored trials is publicly presented in an appropriate and timely fashion and in a fair and balanced manner.
• Working closely with and influencing clinical development on all aspects, including study design, initiation, and monitoring.
• Providing leadership and strategic direction to local Program Leaders in interactions and communications with external customers, key organizations, and institutions.
Required Qualifications:
• MD with at least 5 years of pharmaceutical or biotechnology industry experience in oncology clinical development OR academic clinical research; Board Certification in Medical Oncology is preferred.
• Industry experience in Medical Affairs is preferred.
• Sound scientific and clinical judgment, including in-depth understanding of the scientific method and clinical applications based on medical, scientific, and practical rationale.
• Prior experience and strong history of relationships with academic investigators.
• Strong communication skills and executive presence.
• Strong interpersonal skills with the ability to motivate and influence others, negotiate during situational conflict, and establish the best forward path in the face of competing points of view.
• Proficiency with Veeva and Microsoft Office; in depth Word, PowerPoint & Excel skills.
• Ability to travel (60%).

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Associate Director, Clinical Pharmacology

Job #:02-261

Job Title:  Associate Director, Clinical Pharmacology

Location: Waltham, MA

Role Summary:

Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients by tackling key mechanisms of drug resistance that limit the rate and/or durability of response to existing cancer therapies. Our small molecule drug candidates are directed against an important family of enzymes called kinases, known to be directly involved in the growth and spread of many cancers. We use our deep understanding of kinase biology together with a proprietary chemistry library to purposefully design compounds that maintain kinases in a “switched off’ or inactivated conformation. These therapies comprise tumor-targeted agents designed to address therapeutic resistance causing mutations and immuno-targeted agents designed to control the activation of immunokinases that suppress critical immune system regulators, such as macrophages. We have used our platform to develop a diverse pipeline of tumor-targeted and immuno-targeted drug candidates designed to improve outcomes for patients with cancer by improving the quality, rate and/or durability of their response to treatment. We offer an outstanding culture focused on:

  • Providing a collaborative and energized work environment
  • A diverse and multi-disciplinary workforce
  • Dedicated and talented people who are passionate about achieving excellence in all they do
  • A commitment to the patients we serve

We are seeking an Associate Director, Clinical Pharmacology to contribute to scientific and strategic planning, oversight of projects, management of external vendors, analysis of clinical data, and documentation for NDA-directed development programs for Deciphera’s drug candidates in the area of clinical pharmacology.

This position will report to the Director, Clinical Pharmacology and be located in the Waltham, Massachusetts office.

Key Responsibilities:

  • Act as the lead clinical pharmacologist for one or more oncology programs
  • Work in close partnership with Medical, Clinical Operations, Biostatistics and Translational Research to advance these programs from Phase I to late-stage development
  • Responsible for designing and implementing dose finding strategies to ensure optimal dose and dosing regimens in clinical trials
  • Draft clinical pharmacology components of protocols, investigator’s brochure and other regulatory documents
  • Analyze pharmacokinetic (PK) data and integrate this knowledge into clinical trials and the overall clinical program
  • Oversee bioanalytical analysis, partner with external vendors
  • Provide ad-hoc support to other programs as needed

Required Qualifications:

  • A B.S., M.S., Ph.D., Pharm.D. or equivalent training in pharmacokinetics, pharmaceutical sciences or related disciplines
  • B.S. with 10 years of PK experience, M.S. with 8 years PK experience, or Ph.D./PharmD with 5 years of PK experience.  At least 3-year experience in Clinical Pharmacology
  • Strong understanding of clinical pharmacokinetic concepts
  • Strong technical proficiency in PK analysis (NCA and PopPK)
  • Familiar with PK assay development and sample analysis process
  • Working knowledge of DMPK and Toxicology
  • Effective verbal and written communication skills are essential for the role

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Associate Director, Supply Chain Operations

Job #::04-212

Job Title: Associate Director, Supply Chain Operations

Location: Waltham, MA

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking an Associate Director, Supply Chain Operations, who will have responsibility for implementation of the Company’s supply chain strategy and direct operational management/oversight of end-to-end supply chain networks that support commercialization of our new products. This position represents a key role within Deciphera’s Technical Operations organization, having accountability for key aspects of supply chain management and logistics associated with existing CMOs and the integration of new suppliers, and the implementation of launch strategies by territory to ensure continuity of commercial supply post approval. The successful candidate will work closely with Commercial Operations, Analytics & Insights; Quality Assurance; Regulatory Affairs; and multiple third-party CMOs, commercial packaging organizations and distribution centers. Strong cross-functional team leadership and project management skills are essential requirements of the role.

This position will report to the Senior Director, Supply Chain and be located in the Waltham, MA office.

Key Responsibilities:
• Manage/oversee end-to-end commercial supply chain networks to ensure continuity of supply
• Integrate serialization activities across CMOs, 3PLs and EPCIS service providers
• Serve as integral member of the Commercial Launch Team
• Lead and manage fully integrated launch planning activities with internal stakeholders and global third-party supply chain partners
• Serve as primary point of accountability for commercial inventory control and distribution activities, including production planning/scheduling, CMO oversight, issue resolution, scope change and change implementation
• Collaborate with Commercial Operations, Analytics & Insights to build robust commercial demand/supply models
• Support the development and implementation of commercial distribution plans and return strategies
• Establish and implement supplier performance metrics and routinely monitor key performance indicators (KPIs) to drive operational and economic performance improvement.
• Author policies, procedures and applicable Standard Operating Procedures (SOPs)
Required Qualifications:
• BS in a scientific or technical discipline with 10+ years of supply chain management experience in a regulated cGMP environment.
• Direct experience overseeing commercial contract packaging and labeling organizations and (bio)pharmaceutical CMOs is strongly preferred.
• Candidate must have in-depth knowledge of current Good Manufacturing and Distribution Practices (cGMPs and cGDPs), proficiency with Microsoft PowerPoint and Microsoft Project (or equivalent), and have a demonstrated experience in inventory management, either in a clinical or commercial setting.

Preferred Qualifications:
• Strong vendor/supplier management skills and excellent communication and cross-functional collaboration skills
• Ability to interact with staff (at all levels) in a fast-paced environment, sometimes under pressure, remaining flexible, proactive, resourceful and efficient, with a high level of professionalism and confidentiality
• Ability to work successfully in a team/matrix environment and independently, as required
• Self-motivated, assertive, and self-confident with the ability to act with urgency and passion
• Proven ability to work with a high level of integrity, accuracy, and attention to detail
• Strong organizational skills in order to maintain a high level of productivity, innovation, and priority-setting
• Resourceful, creative, enthusiastic, and results-oriented.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Associate Director, Packaging and Labeling

Job #::04-211

Job Title: Associate Director, Packaging and Labeling

Location: Waltham, MA

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking an Associate Director, Packaging and Labeling, who will be responsible for leading and managing the global packaging and labeling service for Pre-Commercial and Commercial Supply. This role will work with Regulatory Affairs and Medical Affairs to define product labeling and package graphics requirements for new commercial products and with the Marketing Team to assist in design graphics for marketing materials. This position will also be responsible for overseeing the operational aspects of commercial supply labeling, including serialization, label copy, draft labeling, proofreading, electronic and hard copy file maintenance, and distribution of approved materials. The position will be required to work closely with several functional departments including Technical Operations, Commercial Operations, Marketing, Quality Assurance, Regulatory Affairs and Third-Party Vendors, CMOs (Commercial Packaging Vendors and Print Vendors).

This position will report to the Senior Director, Supply Chain and located in the Waltham, MA office.

Key Responsibilities:
• Create and revise labeling for product labels, packaging materials, and instructions for use that meet medical, legal, and regulatory requirements.
• Work with Regulatory Affairs and Supply Chain Operations on label copy changes, draft labeling and inventory management post approval.
• Evaluate and select any labeling systems or software to determine the impact of implementation to the business for label copy review and repository if required.
• Coordinate language translation activities, as required, and facilitate the review, approval, and release of all labeling components from development to commercialization.
• Create artwork for new products / launches (clarification of specific branding and regulatory requirements on introduction of new products e.g. serial labeling, registered printing, etc).
• Develop, establish, and maintain global packaging standards (artwork, process, compliance) to leverage internal and external capabilities.
• Manage the authoring of necessary procedures, design/approval of packaging specifications and drawings, generation of packaging artwork, and applicable Standard Operating Procedures (SOPs).
• Collaborate with the Supply Chain Operations Team with implementation, documentation and maintenance of commercial pack-out designs, serialization, barcodes and shipping labels.
• Maintain knowledge of new and current packaging and labeling technologies and emerging pharmaceutical compliance initiatives, such as UDI (Unique Device Identification) requirements.
• Assist regulatory team with NDC coding, NDA module one labeling, draft labeling process and monitoring FDA guidelines and requirements for label control.

Required Qualifications:
• AD/BA in graphical design or equivalent with 5+ years design artwork related experience in the healthcare environment
• Direct experience in pharmaceutical or device artwork design preferred.
• Working knowledge of FDA regulations related to New Drug Applications, Good Manufacturing Practices, and Product Labeling.
• Proficient knowledge of artwork development and management applications as well as Microsoft Excel, PowerPoint and Project software required.
• Proficient knowledge of Adobe InDesign, Adobe Illustrator and Microsoft Suite of software required

Preferred Qualifications:
• Understanding of commercial pack out designs and serialization
• High attention to detail and demonstrated ability to manage multiple critical path projects concurrently
• Ability to develop, implement and monitor a metrics performance package for labeling and packaging activities
• Demonstrated understanding of quality management and documentation systems – especially as related to change control process and product specifications
• Demonstrates flexibility through adapting to external environment influences through development of new strategies and tactics
• Excellent communication and influencing skills, strong collaboration skills

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Senior Director/Director, Investor Relations

Job #::03-219

Job Title: Senior Director/Director, Investor Relations

Location: Waltham, MA

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
The Deciphera Investor Relations position is a newly created role that will report to the Chief Financial Officer. This position will be a key strategic partner to the CFO, and will have responsibility for strategic and tactical leadership of Deciphera’s investor relations function and play an important role in developing the company’s financial communication strategy. This role’s mandate is to ensure consistent messaging across all investor relations platforms including developing and managing strong relationships with the investment community including investors, analysts, and other investment community stakeholders and influencers. The Investor Relations leader will successfully integrate the investor relations work into the broader long-term corporate finance strategy. The successful candidate will have a strong track record of successfully creating and helping to present a clear message of value and impact to the investment community.

This position will report to the Chief Financial Officer and be located in the Waltham, MA office.

Key Responsibilities:
• Partner with the CFO to develop the Deciphera Investor Relations strategy.
• Execute and drive the company’s investor relations strategy including collaborating with leadership team and key stakeholders to define strategic communications delivered to investors, analysts, and the public.
• Assess company, peer group, and industry factors to develop materials and communication strategy for quarterly and annual reporting, press releases, presentations, briefing information, Q & As, and other external presentations.
• Maintain comprehensive, current knowledge of Deciphera’s research and development approaches and business strategies to better inform IR strategy.
• Develop and help manage relationships and maintain regular communication with investors to provide up-to-date information about company’s progress as well as information about market trends.
• Monitor and analyze data on trading activity, relevant industry data, and competitor performance to ensure Deciphera is strategically positioned for success.
• Plan, manage, and oversee external events including investor meetings.
• Serve as primary point of contact for investor inquiries.

Required Qualifications:
• Bachelor’s degree required, with advanced degree in business or finance preferred.
• 8-10 years of communications and/or investor relations experience with at least 2+ in a public, commercial-stage biotech or biopharmaceutical company.
• Communications experience in the investment community or in an IR firm focused on the life sciences sector also applicable.
• Outstanding written and verbal communication skills including presentation skills.
• A proven ability to effectively interact with and present to external and internal stakeholders.
• Ability to translate complex financial and investment information.
• Established relationships and credibility with the investment community.
• Uncompromising ability to maintain confidentiality, exercise sound judgement, and the highest level of discretion.
• Ability to analyze complex issues to develop relevant and realistic plans, programs, and recommendations that resolve issues and mitigate risks.
• Ability to adapt to dynamic and evolving priorities and respond to variable timelines with accuracy and urgency.
• Knowledge of SEC and disclosure requirements preferred.
• Experience planning and facilitating investor events.
• Self-direction, creativity, strategic thinking, and willingness to be hands-on.
• Eagerness to and ability to work in a dynamic, fast-paced environment while remaining flexible, proactive, and resourceful.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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National Director, Medical Science Liaison

Job #::02-260

Job Title: National Director, Medical Science Liaison

Location: Remote/Field Based

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking a National Director, Medical Science Liaison (MSL) who will have overall responsibility for building, leading, managing, and supporting the US MSL field team and will report to the VP of Medical Affairs. Together with the VP of Medical Affairs, the National Director, MSL will build the team and establish the long‐term vision, strategy, plans, objectives, and infrastructure for the MSL team. The successful candidate will have significant experience facilitating strong MSL relationships with the external scientific and medical community.

This position will report to the VP of Medical Affairs and be located in the Waltham, MA office.

This is a remote/field-based position, up to 50% travel is required.

Key Responsibilities:
• Lead and build the Medical Science Liaison capability for Deciphera.
• Identify candidates, hire, train, develop, and manage a team of MSLs to implement field initiatives ensuring the development of best practices and scientifically‐based materials that are compliant with all legal and regulatory and company guidelines.
• In collaboration with key internal stakeholders, lead the development and execution of Deciphera’s external engagement and educational strategies for centers of excellence, HCP’s, and thought leaders.
• Lead medical education through communication of scientific information.
• Ensure high quality presentations of scientific data in various settings, including advisory boards, investigator meetings, to enhance product/disease state knowledge.
• Provide support to clinical operations for investigators in ongoing clinical trials, investigator-initiated research, and registries consistent with company objectives and regulations.
• Lead Deciphera’s medical team at national and regional scientific meetings including staffing medical affairs booths, gathering competitive intelligence, and developing pre and post‐conference scientific materials.
• Identify key deliverables, insights, and metrics that highlight the value of the MSL organization and communicate with senior leadership at Deciphera on an ongoing basis.
• Track and provide quantitative and qualitative data from MSL activities that demonstrate customer impact to the Deciphera organization and ensure goal achievement.

Required Qualifications:

• PharmD, PhD, or MD preferred. Advanced degree Nurses, NPs, PAs, or those with a Masters’ degree in life sciences with pharmaceutical industry and clinical research experience are also welcome to apply.
• Minimum 10 years of relevant biotech/pharmaceutical industry experience, oncology experience preferred.
• Exceptional leadership/management skills; 8 years of experience leading field based MSL’s teams.
• Thorough understanding of applicable federal and state regulatory requirements for field‐based scientific personnel; successful track record of compliance.

• Experience/expertise in interpretation of scientific data, market research, competitive intelligence tools, drug information systems, and developing medical educational strategies.
• Outstanding written and verbal communication/listening and presentation skills.
• Previous success translating/tailoring complex scientific concepts into simple language for targeted audiences.
• Demonstrated problem solving abilities and strong organizational skills.
• History of collaboration/teamwork; reputation for successful partnering with internal and external stakeholders, including medical opinion leaders, large group practices, medical directors and MCO professionals.
• Good understanding of clinical development and commercial environment.
• Ability to work successfully in a team/matrix environment and independently, as required.
• Pragmatic, solution-oriented thinker who possesses a “can do” and” whatever it takes” attitude, coupled with excellent organizational and communication skills.
• Strong interpersonal skills with the ability to motivate and influence others, negotiate during situational conflict, and establish the best forward path in the face of competing points of view.
• Proficiency with Veeva and Microsoft Office; in depth Word, PowerPoint & Excel skills.
• Ability to travel (50%).

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Sr Manager/Assoc Director, Global Health Economics and Outcomes Research (HOER)

Job #:02-259

Job Title: Senior Manager/Associate Director, Global Health Economics and Outcomes Research (HEOR)

Location: Waltham, MA

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
This position will report to the VP Health Economics & Outcome Research and Market Access and be located in the Waltham office.

Key Responsibilities:
• Support development of clear, compelling and differentiating payor value messages for our medicines
• Provide input into clinical plans regarding HEOR endpoints and ensure follow-up during trials to ensure accurate and complete collection of HEOR data
• Develop and maintain strong relations with Market Access, Business Analytics, and Statistics groups
• Work with cross-functional partners to develop thoughtful and informative insights regarding the economic consequences and impact to patient-outcomes of Deciphera’s products, in a way that is aligned to the objectives of Deciphera
• Leverage research findings to develop tools useful for payors and other stakeholders (e.g., budget impact models, cost-effectiveness models, survival models)
• Leverage data such as: longitudinal electronic medical records, pharmacy data, and medical claims
• Pursue excellence in quality of design, execution and publication of real-world health outcomes studies for ripretinib and the pipeline
• Ensure compliance with regulatory and legal policies when conducting and disseminating research
• Assume overall accountability for vendor deliverables
• Collaborate with field force to maintain an updated HEOR tool kit and dossier and anticipate the evolving payor response to ripretinib
• Periodically train colleagues such as the account management team, field force and global teams on HEOR results, value messages, and tools, and serve as a valued and responsive resource to them
• Work to disseminate results in a suitable format, such as dossiers, manuscripts, posters and Excel tools
• Ensure compliance with regulatory and legal policies when conducting and disseminating research
• Participate in projects unrelated to HEOR, as the need arises

Required Qualifications:

• Graduate degree required; formal training in economics, epidemiology, physics, statistics, health economics, outcomes research, health services research, or other similarly relevant field of study with emphasis on useful mathematical modeling
• Strong analytical skills including experience in designing and creating mathematical models of complex systems
• Experience using VBA, Matlab, R, or SAS

Preferred Qualifications:
• Additional helpful experience and skills
• Understanding of regulatory standards for communication of health outcomes data in the US
• Previous HEOR experience in the pharmaceutical/biotech industry
• Past roles in strategy, account management or other business planning role
• A cross-functional orientation and ability to partner with colleagues
• Results-orientation with excellent interpersonal, communication and presentation skills
• Travel is expected to be less than 10% on average, but may be frequent around product launch
• Strong commitment to business ethics and teamwork

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Associate General Counsel, Commercial and Chief Compliance Officer

Job#::03-218

Job Title: Associate General Counsel, Commercial and Chief Compliance Officer

Location: Waltham, Massachusetts

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking an Associate General Counsel, Commercial and Chief Compliance Officer to (i) support the Commercial function, including acting as our brand lawyer, counseling the Commercial team on marketing programs, ad/promo reviews, promotional review committee membership, distribution agreement reviews, and overall healthcare law compliance for traditional pre-launch activities (ii) support the Medical Affairs team and patient advocacy functions, and (iii) support the development and implementation of Deciphera’s global corporate compliance program, including development and implementation of relevant policies, procedures, training and auditing and monitoring programs, and acting as Chief Compliance Officer. This person will serve as the company’s subject matter expert in the areas of healthcare law and compliance, including all rules and regulations of the FDA, OIG and CMS, and all applicable anti-kickback, privacy, fraud and abuse, anti-bribery, Sunshine Act and product liability statutes and regulations.

This position will report to the General Counsel and be located in the Waltham, MA office.

Key Responsibilities:
• Lead the development and implementation of legal support for the Commercial, Medical Affairs and Patient Advocacy functions, as the lead brand lawyer, including marketing and promotional reviews, and healthcare law compliance.
• Lead the development and implementation of Deciphera’s global corporate compliance program, including development and implementation of relevant policies, procedures, training and auditing and monitoring programs.
• Serve as the company’s subject matter expert in the areas of healthcare law and compliance, including all rules and regulations of the FDA, OIG and CMS, and all applicable anti-kickback, privacy, fraud and abuse, anti-bribery, Sunshine Act and product liability statutes and regulations.
• Review and advise on programs, initiatives, and contracts related to sales, marketing reimbursement, market access, government price reporting, pricing, and non-promotional education.
• Review and advise on promotional materials, sales training materials, federal and state government price reports, and corporate communications.
• Serve as the leader of the company’s Compliance Committee.
• Identify training needs within the organization and develop and present training sessions on relevant laws and legal/business issues.
• Assist and advise in the conduct of internal investigations.
• Provide due diligence and integration support in connection with business development transactions.
• Stay abreast of and communicate to the organization all significant pending and actual decisions, legislation and regulatory rulings that may affect the company in the area of commercial healthcare law.
• Establish a rapport and a positive working relationship with management and personnel at all levels, particularly within the home office and field-based Commercial organization, to encourage and continue the proactive use of in-house legal counsel.
• Supervise external legal counsel.
• Build compliance function and systems to support same.

Required Qualifications:
• J.D. from a law school accredited by the American Bar Association (ABA).
• Admitted to practice law in one or more states.
• At least 10 years of related experience within a commercial stage pharmaceutical or biotech company or law firm equivalent.
• Large law firm experience helpful.
• Expertise in the areas of corporate compliance, commercial healthcare, and FDA regulatory law and regulation, including with respect to FDA labeling and promotional matters, healthcare fraud and abuse laws, pricing and reimbursement issues, U.S. and international transparency laws and regulations, privacy laws, anti-bribery laws, and other laws and regulations related to the development and commercialization of pharmaceutical products.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Clinical Project Manager

Job #:02-258

Job Title: Clinical Project Manager (CPM)

Location: Waltham, MA

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

We are seeking a Clinical Project Manager to manage clinical trials from initiation to completion through leading internal and external cross-functional disciplines.

This position will report to the VP, Clinical Operations and be located in the Waltham, MA office.

Key Responsibilities:
• Responsible for the operational implementation of pre-market and post-market clinical trials
• Develop and manage the project plan and timeline, which may include budget planning
• Manage escalation of study-related issues and communicate as appropriate with management
• Select and manage clinical trial vendors such as CROs and external laboratories, and ensure their performance is consistent with Deciphera standards
• Collaborate with clinical supply team on selection and management of an IxR vendor
• Provide input and coordinate the on-schedule delivery of clinical trial supplies in collaboration with clinical supply team and relevant vendors
• May perform periodic visits to investigational sites and CROs to assess study progress and compliance
• Assist and participate in planning and conduct of investigator meetings
• Oversee the authoring and management of study-related plans and manuals (e.g. project management plan, site monitoring plan, safety management plan, patient recruitment plan, risk management plan, data management plan, study reference manual, regulatory binder, central lab manual, pharmacy manual, statistical analysis plan, etc.)
• Facilitate the development of study templates such as investigational study budget, informed consent form, and source documents
• Participate in the development of study protocols by coordinating with the medical writer
• Participate in authoring the clinical study report as well as the clinical portion of regulatory submissions
• Participate in review of scientific abstracts and manuscripts
• Select and manage investigational sites
• Serve as a resource for vendors, site coordinators, investigators, and other staff members regarding investigational products and protocols
• Ensure site monitoring is sufficient such that documentation from investigators and investigational sites meets FDA/GCP/ICH requirements and fulfills the study objective
• May review clinical monitoring reports and related correspondences
• Provide input on case report form design and EDC system requirements
• Monitor the status of clinical data collection and query trends
Required Qualifications:
• Bachelor’s degree in health profession and/or science
• A minimum of 3 years of relevant clinical operations experience in the pharmaceutical industry and/or CRO
• Excellent verbal and written communications skills
• Self-motivated, with strong organizational skills and attention to detail
• Computer proficiency in MS Office (i.e. Word, Excel, PowerPoint, project)
• Ability to travel approximately 20%

Preferred Qualifications:
• Bachelor’s degree in health profession and/or science
• A minimum of 3-4 years of relevant clinical operations experience in the pharmaceutical industry (oncology experience)
• Excellent verbal and written communications skills
• Self-motivated, with strong organizational skills and attention to detail
• Computer proficiency in MS Office (i.e. Word, Excel, PowerPoint)
Ability to travel approximately 20%

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Vice President, Corporate Development and Alliance Management

Job #::03-217

Job Title: Vice President, Corporate Development and Alliance Management

Location: Waltham, MA

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking a Vice President of Corporate Development and Alliance Management to lead and manage the company’s corporate partnerships and alliances from the research phase through clinical development and into commercialization. The strategic and pivotal nature of this role requires an individual who can effectively and efficiently partner with the Chief Business Officer (CBO) and across the Executive Management Team to maximizing the strategic value of the Company’s portfolio of drug product candidates. While a strong deal sheet of successfully completed transactions will be an important factor in selecting the individual for this new role, the ability to identify, assess and understand the nuances required to craft transactions that build long term value is a critical capability.

This position will report to the Chief Business Officer and be located in the Waltham, MA office.

Key Responsibilities:
• Design and execute partner outreach campaigns, and drive discussions to identify potential partnering and M&A opportunities that support of the Company’s strategic goals and maximize the value of the Company’s portfolio of drug product candidates.
• Lead and inspire cross-functional teams to evaluate partnership opportunities and undertake due diligence to industry leading standards.
• Develop appropriate deal structures, term sheets, benchmarking and valuation models to assess and inform both the evaluation of opportunities and subsequent negotiations.
• Communicate effectively and timely with the CBO and the Executive Management Team regarding the status, timing, key events, and revisions to corporate development activities.
• Create agendas, minutes, materials and dashboards to support and communicate corporate development activities.
• Prepare and present information and materials to the Executive Management Team and potentially to the Board of Directors on potential partnership opportunities.
• Work with the CBO and legal counsel to develop negotiation strategies and positions, draft and review term sheets and contractual agreements, and lead negotiations to closure.
• Manage existing alliances, including their governance structures and mechanisms for dispute escalation.
• Continuously assess and benchmark the Company’s corporate development and alliance management practices and activities to ensure that these are at industry leading standards.
• Participate in Portfolio Strategy Steering Committee and Program Team Meetings as the key representative from Corporate Development.

Required Qualifications:
• B.S./M.S. degree in a life sciences discipline; advanced degree and/or MBA strongly preferred.
• A minimum of 15 years relevant experience in the biopharmaceutical industry, including a minimum of 10 years transactional experience in business/corporate development.
• A strong network of business development contacts within the biotechnology and pharmaceutical industry.
• Deep understanding of the drug development process, including strategic and operational aspects; significant experience within oncology strongly preferred.
• Deal sheet and proven track record of successfully leading, negotiating and delivering high value corporate partnerships and/or M&A.
• Strong analytical skills with a thorough understanding of financial evaluation techniques (commercial forecasting, deal analyses, P&L modeling, NPV, etc.).
• Self-directed, accomplishment-driven individual with a strong sense of passion and urgency who can work both independently and in a cross-functional team environment, fostering open communication, mutual understanding and cooperation.
• Pragmatic, solution-oriented thinker who possesses a “can do” and ”whatever it takes” attitude, coupled with excellent organizational and communication skills.
• Strong interpersonal skills with the ability to motivate and influence others, negotiate during situational conflict, and establish the best forward path in the face of competing points of view.
• Proven ability to be productive and successful in an intense work environment.
• Ability to articulate complex issues and ideas with clarity.
• Ability and willingness to undertake significant travel.
• Fluency with standard computer software packages (MS Word, Excel, PowerPoint, and Project). Experience with deal valuation tools and/or software applications is a plus.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Associate Director, New Product Planning

Job #::03-216

Job Title: Associate Director, New Product Planning

Location: Waltham, MA

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking an Associate Director/ Director, New Product Planning who will drive key business decisions by providing data driven strategic input to shape the early commercial strategy of preclinical- and early clinical-stage assets across the company’s pipeline of novel kinase switch control inhibitors. This new position will collaborate closely across functions within the organization including research, development, program management, clinical development, clinical operations, regulatory, business development, and commercial. The role offers a candidate the opportunity to significantly contribute to the long-term commercial success of the portfolio, and is responsible for providing commercial input and evaluation into key early stage product planning opportunities, and includes early market research and business intelligence activities, as well as initial competitive positioning and preferred product presentation. The ideal candidate should have experience working in product marketing, business intelligence or commercial analytics within a biotech or pharmaceutical company. While the position reports to the Chief Business Officer, the role requires particularly close collaboration with the commercial group reporting into the Chief Commercial Officer.

This position will report to the Chief Business Officer and be located in the Waltham, MA office.

Key Responsibilities:
• Work cross-functionally with the various program teams to conduct robust and rigorous market assessments on key oncology disease areas and the opportunities for pre-clinical- and early clinical-stage assets.
• Provide commercial input and strategic guidance to cross-functional program teams to inform key business and development decisions.
• Communicate key disease area/market insights to relevant internal stakeholders, identifying considerations and implications for Deciphera’s pipeline plans.
• Identify gaps in internal understanding of target diseases and create and execute plans to address gaps through primary and/or secondary market research.
• Construct validated market assessments and forecasts for potential label indications for pre-clinical- and early clinical-stage assets.
• Develop and propose early commercial strategies, value propositions and a prioritized approach to potential label indications.
• Collaborate with internal stakeholders (primarily the commercial group) to develop, update and maintain Target Product Profiles (TPPs) for Deciphera’s early oncology assets.
• Develop and maintain early asset dashboards for communications to Senior Leadership on visions, strategies, opportunities, challenges, risks and tactical activities for Deciphera’s early oncology assets.
• Develop and maintain strong, internal partnerships with cross-functional colleagues (e.g. commercial, regulatory, CMC, clinical, business development, research etc.).
• Provide commercial input on business development asset evaluations.
• Participate in the various program team meetings for Deciphera’s early oncology assets.

Required Qualifications:
• B.S./M.S. degree in a life sciences discipline; an MBA strongly preferred.
• A minimum of 6-8 years relevant commercial experience in the biopharmaceutical industry including a minimum of 3-4 years new product planning or equivalent experience in oncology.
• Strong understanding of the drug development process in oncology including the strategic and operational requirements.
• Ability to synthesize findings and clearly articulate implications from multiple sources of information, including primary and secondary market research and data, and formulate strong, supportable recommendations.
• Self-directed, accomplishment-driven individual with a strong sense of passion and urgency who can work both independently and in a cross-functional team environment, fostering open communication, mutual understanding and cooperation.
• Pragmatic, solution-oriented thinker who possesses a “can do” and ”whatever it takes” attitude, coupled with excellent organizational and communication skills.
• Proven ability to be productive and successful in an intense work environment
• Fluency with standard computer software packages (MS Word, Excel, PowerPoint, and Project). Experience with forecast and valuation models and/or software applications a plus.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Director, Program Management

Job #::03-214

Job Title: Director, Program Management

Location: Waltham, MA

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking a Director, Program Management who will have responsibility for directing and supporting cross-functional program teams within a matrix environment that are engaged in the development of the company’s pipeline of novel kinase switch control inhibitors. The successful candidate will be assigned multiple programs which may vary from preclinical stage through late stage development, including projects with planned drug applications for marketing authorizations. The role requires a strategic leader who is experienced in drug development and understands the inherent process, its complexity and its interdependencies. A key component in the successful execution of this role will be cultivating strong, constructive and proactive relationships across the project management roles that exists within line functions (CMC, Regulatory Affairs, Commercial, Clinical Development, Pre-clinical Research etc.). Through facilitation of cross-functional program teams, this role is accountable for establishing for each program an integrated cross-functional development strategy that includes excellence with respect to: timelines; dashboards and tools that provide transparency; budget inputs; identifying/highlighting risks and creating mitigation and/or contingency plans; and the attainment of key business goals/milestones. In addition, this individual will also support efforts to balance competing priorities within the portfolio and assure consistent standards are met across projects.

This position will report to the Chief Business Officer and be located in the Waltham, MA office.

Key Responsibilities:
• Develop and maintain fully integrated project plans (Gantt), incorporating activities, responsibilities, interdependencies, key resource requirements and critical path analysis that facilitate the delivery of tangible results against program and corporate goals.
• Work closely with function-based colleagues with project management/timeline responsibilities to ensure accuracy, consistency and continuity between the integrated project plan and timelines within those key functions (e.g. commercial, regulatory, CMC, clinical, business development, research etc.).
• Direct and facilitate program teams to identify, define, prioritize and communicate risks to successful program execution; develop and monitor risk mitigation and contingency plans.
• Communicate effectively and timely with program team members and senior management regarding project status, timelines, milestones, key events, and revision to the development plan.
• Create agendas, minutes, materials and dashboards to support and facilitate the project team’s management and execution of the development plan.
• Establish and implement operational mechanisms to facilitate effective and timely cross-functional communication and decision making, and successful execution of the development plan.
• Lead data-driven decision-making processes to enable timely and objective recommendations for continuation, acceleration, reprioritization, redesign of the development plan.
• Liaise with peers within the program management function to maintain consistent cross-project standards and to determine overlap of competing priorities.
• Serve as an integral member of the program management function, ensuring cross-functional alignment of program strategies.
• Develop project budget assumptions and resourcing needs; monitor, report and escalate unresolved issue and deviations in a time appropriate manner to the Portfolio Strategy Steering Committee and/or senior management.
• Participate in Portfolio Strategy Steering Committee meetings as the key representative of the program team.

Required Qualifications:
• B.S./M.S. degree in a life sciences discipline; advanced degree and/or MBA strongly preferred.
• A minimum of 10 years drug development experience in the biopharmaceutical industry including a minimum of 5 years project management or equivalent experience.
• Strong understanding of the drug development process in oncology including the strategic and operational requirements.
• Proven track record of success in leading and managing cross-functional development teams. Prior experience managing project to NDA submission a plus.
• Competency in developing, implementing and delivering project plans (Gannt), dashboards and risk mitigation and contingency plans to successful endpoints.
• Self-directed, accomplishment-driven individual with a strong sense of passion and urgency who can work both independently and in a cross-functional team environment, fostering open communication, mutual understanding and cooperation.
• Pragmatic, solution-oriented thinker who possesses a “can do” and ”whatever it takes” attitude, coupled with excellent organizational and communication skills.
• Strong interpersonal skills with the ability to motivate and influence others, negotiate during situational conflict, and establish the best forward path in the face of competing points of view.
• Proven ability to be productive and successful in an intense work environment
• Ability to articulate complex issues and ideas with clarity to enable understanding and timely decision making.
• Fluency with standard computer software packages (MS Word, Excel, PowerPoint, and Project). Experience in other project management tools or software applications a plus.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Senior Manager, Publications

Job #::02-256

Job Title: Senior Manager, Publications

Location: Waltham, MA

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking a Senior Manager, Publications to develop publications plans, drive the execution of publication projects of assigned products, and support other activities as needed.

This position will report to the VP, Medical Affairs and be located in the Waltham, MA office.

Key Responsibilities:
• Collaborate with Medical Affairs and various cross functional teams to develop publication plans of assigned programs.
• Leads the planning, execution and delivery of publication projects to ensure high quality and timely delivery of scientific publications.
• Coordinate the review, approval, and other applicable activities related to the development and submission of the publication projects.
• Interfaces with external experts (e.g., physicians, other health care professionals) and internal Deciphera functions (e.g., Clinical, Medical Affairs, Statistics, Data Management, R&D, Regulatory) to ensure accurate and timely completion/delivery of information
• Provide hands on medical writing and editorial work, as well as content and editorial support for select publications, ensuring successful creation of high-quality presentation-ready documents at the direction of Med. Affairs leadership and publication authors.
• Ensure documentation of compliance with authorship and publication guidelines as stipulated by the International Committee of Medical Journal Editors (ICMJE) and Good Publication Practice for Communicating Company-Sponsored Medical Research (GPP).
• Work with and oversee publication vendors to ensure deliverables are of high quality, delivered in a timely manner, and in budget.
• Liaise with internal and external stakeholder, including authors, researchers, investigators, medical leads, R&D clinical leads and biostats.
• Lead study publication committee discussions, including monthly, quarterly, and yearly publication update meetings as needed.
• Prepare and manage publication budget for assigned product, collaborate with Finance to coordinate the processing and reporting of all financial activities.
• Support global medical communication plan development by collaborating with team
• Lead and facilitate Publication Review Committee(s) discussion.
• Manage vendor budget and activities and Oversee the quality and timeline of vendor work.

Required Qualifications:
• PharmD, or PhD in Health Sciences preferred; Bachelor’s Degree or Advanced Degree in Health Sciences may be considered based on years of experience/qualifications.
• Minimum of 3 + years of pharmaceutical industry publications experience or experience working for a Publications Vendor
• Proven track record of working successfully with cross-functional teams to achieve goals. Experience with publication planning is required.
• Experience with clinical trials and international work experience are preferred.
• Excellent written and oral communication skills, particularly strong formal presentation skills; strong interpersonal skills; possession of strong scientific analytical skills; excellent planning and organizational skills; experience in managing budgets; understanding of good publication practices and guidance;
• Basic knowledge of clinical development process and appropriate application of biostatistics; Oncology experience is strongly preferred; proficiency using standard software suites

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Contracts Manager

Job #: :03-215

Job Title: Contracts Manager

Location: Waltham, MA

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking a contracts professional to join our growing legal team. This person will manage contracts and serve as a business partner for various departments. Under the supervision of the Associate General Counsel, this individual will work with the business to identify and mitigate legal risk and manage a variety of contracts. This is an exciting opportunity to both build and manage the contracting needs of a growing biotech company.

This position will report to the Associate General Counsel and be located in the Waltham, MA office.

Key Responsibilities:

• Evaluate and effectively manage business timelines and goals to ensure quality legal support.
• Collaborate with business functions, including finance, regulatory, supply chain and program management to manage various legal initiatives, contracts, and other projects through completion.
• Responsible for building, managing and implementing the contract process from beginning to end, including communicating and corresponding with internal clients, vendors and other stakeholders, drafting contract language, negotiating with external parties, and ensuring proper tracking, execution and filing of contracts.
• Draft, review, and negotiate a wide variety of agreements, including confidential disclosure agreements, clinical trial agreements, master services agreements, consulting agreements, quality agreements, and work orders.
• Correspond, communicate, and build relationships with internal clients, CROs and vendors.
• Identify and address legal and compliance risks and find solutions to mitigate these risks.
• Assist with the selection and implementation of contracts management database.

Required Qualifications:

• Bachelor’s degree required.
• Excellent execution and follow through skills.
• Experience drafting and negotiating legal language in transactional agreements, some experience with master service agreements and/or consulting agreements preferred.
• Demonstrated expertise in either managing clinical trial agreements or supporting clinical operations functions and clinical study-related issues.
• Experience in a commercial organization strongly preferred.
• Minimum 8 years’ experience working with contracts.
• Outstanding attention to detail and ability to identify business and legal issues.
• Excellent analytical, organizational, and project management skills.
• Manage special projects and performing other duties as assigned by attorneys.
• Perform all other related duties as assigned.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Director, Global Medical Affairs Excellence

Job #::02-257

Job Title: Director, Global Medical Affairs Excellence

Location: Waltham, MA

Role Summary:

Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking a Director of Global Medical Affairs Excellence to set the strategic direction for the Medical Affairs department and lead operational efforts to drive annual and longer-term strategic planning and execution of Medical Affairs activities. In addition to strategic and tactical plans, this individual will strongly contribute to the establishment of key processes underlying the execution of core Medical Affairs activities including management of grants, medical education, publications planning and execution, medical training, meeting planning and thought leader engagement. This person will have direct responsibility of hiring and managing a team of direct reports.

This position will report to the Vice President of Medical Affairs and be located in the Waltham, MA office.

Key Responsibilities:
• Manage annual and longer-term strategic planning and goal development and tracking, annual budgets, and information system requirements and associated reporting capabilities
• Manage budgets and contracting for a variety of Medical Affairs activities, including grants, medical education, training, medical congress activities and other scientific meetings, and investigator-sponsored research
• Ensure that as Medical Affairs is established and grown, and becomes an integrated, coordinated, and high-functioning team
• Manage high-profile initiatives to enable the Medical Affairs team to operate efficiently and effectively in the context of continuous improvement
• Ensure all projects are on track through partnership with the cross-functional teams
• Work within cross-functional teams and amongst all corporate functions to ensure smooth operations across Medical Affairs
• Identify technical needs and work with IT to evaluate and implement software solutions as group needs evolve
• Contribute to the establishment of Medical Affairs policies, business processes and SOPs (as necessary)
• Apply project management best practices across Medical Affairs
• Ensure that Medical Affairs team members are trained on all relevant SOPs and that Medical Affairs activities are conducted in a compliant manner


Required Qualifications:
• Bachelor’s degree or higher in a scientifically related field; PharmD, Advanced Masters or MBA preferred.
• 8+ years of relevant experience in a pharmaceutical or biotech company
• Experience in project management or operational management
• Experience hiring and managing teams of medical affairs professionals
• Detail-oriented
• Demonstrated organizational skills and ability to manage multiple complex/layered projects and competing priorities
• In depth understanding of Medical Affairs activities and the regulatory environment in which we operate
• Flexible and willing to take on a variety of responsibilities as the needs of the Medical Affairs team grow and evolve
• Able to demonstrate exceptional follow-through on tasks and projects

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Manager/Senior Manager, Information Management

Job #:03-212

Job Title: Manager/Senior Manager, Information Management

Location: Waltham, Massachusetts

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking an Manager/Senior Manager, Information Management to provide technical and hands-on leadership. A successful Manager/ Senior Manager would be a fast learner that can understand the company’s operations to provide support and expand services. We are looking for a hands-on manager that can assist in various projects as well as providing technical feedback for the team members.

This position will report to the Associate Director of Information Technology in Waltham, MA.

Key Responsibilities:
• Primary system administrator in the company for planned application development and system implementation, administration, migration and training of a Veeva Vault Information Management solution for current and new employees and contractors.
• Monitor alerts and troubleshoot critical production issues impacting end-users, including system unavailability and data integrity issues.
• Provide training and mentoring with multiple departments into the use and abilities of Information Management solutions.
• Work with project team members in the selection, development, testing, validation, training, implementation and ongoing support of business systems.
• Participate in User Acceptance Testing, as well as oversee and participate, as needed, in Installation Qualification (IQ), Operational Qualification (OQ) and Performance Qualification (PQ). IQ/OQ/PQ.
• Implements policy directives and instructions to manage information through its life cycle regardless of media.
• Primary contact and administrator for multiple platforms and vendors to ensure quality of deliverables.
• Provide support to developers during regular code releases.
• Assist with the development and implementation of SOPs, training materials, system job aids, work instructions and help guides.

Required Qualifications:
• Bachelor’s degree in Computer Science or related field.
• 5+ years IT experience in the life sciences industry
• Veeva Vault Certified Administrator with a minimum of 2 years’ experience configuring Veeva Vault and an excellent understanding of all available Veeva modules.
• Strong software proficiency with Microsoft Office, Starting Point and other desktop applications on both Mac and PC (Windows 10) operating systems.
• Evaluate new technologies that relate to the IT strategy.
• Experience implementing new Enterprise Systems.

Preferred Qualifications:
• Experience with PleaseReview administration.
• Knowledge of database management system (DBMS) solutions to create, retrieve, update and manage data.
• Provide training and educational opportunities for new IT services and trends to employees.
• Pharmaceutical or scientific knowledge to help evaluate and expand clinical services.
• Strong organizational skills to help maintain current IT projects and progress.
• Excellent verbal and written communication skills.
• Strong interpersonal skills to establish a good working relationship with colleagues, while maintaining professional standards.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Information Technology System Architect

Job #:03-211

Job Title: Information Technology System Architect

Location: Lawrence, Kansas

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking IT Systems Architect to be responsible for working with the IT Team and application owners to ensure all requirements are understood and translated to technical solutions. Additional responsibilities will include working with to optimize Network, Security, Storage, and Communications operations. This person will plan, coordinate, and design Cloud service activities for the organization, as well as provide administrative direction for the IT operations group. Work closely with decision makers in other departments to identify, recommend, develop, implement, and support cost-effective technology solutions. Define and implement appropriate IT policies, procedures, and best practices.

This position will report to the Director of Information Technology and be located in the Lawrence, Kansas office.

Key Responsibilities:
• Maintain and upgrade existing Microsoft Server domain across multiple locations.
• Design, implement and maintain a hybrid network cloud strategy with cloud technologies such as AWS and/or Azure and on-site network infrastructure to support the growing needs of the company and provide continuous improvement.
• Define current services that can be migrated to the cloud for cost savings and enhancing end user productivity like low cost disk for static data, Dev/Test environments, and Cloud data storage like OneDrive for Business, Box or Veeva Vault.
• Contribute to Information Technology group operations and planning, including fostering innovation, planning projects, and organizing and negotiating the allocation of resources.
• Assist in developing the necessary policies and procedures, including those for architecture, security, disaster recovery, standards, and service provision.
• Comfortable with remote server management, network/wireless design and managing access to SaaS applications.
• Creates and maintains documentation for systems and solutions as they are installed and upgraded. Publishes the documentation to shared repositories and updates repository.
• Other duties as assigned.

Required Qualifications:
• Bachelor’s degree in Computer Science, or related field.
• 5+ years IT experience in enterprise network and server environments.
• Technical knowledge of infrastructure technology both on premise and Cloud based, including server management, LAN/WAN/Wireless networking (Cisco & Meraki), storage, security (Meraki and SonicWall), SSL and site-to-site VPN communications, etc.
• Experience implementing and supporting enterprise solutions such as O365, AWS, Azure, SharePoint, and Active Directory.
• Good experience with security audited environment.
• Evaluate new technologies that relate to the IT strategy.
• Some travel might be needed between Lawrence, KS and Boston office.
• Occasionally lifts/carries objects and materials weighing +30 pounds.

Preferred Qualifications:
• Strong Proficiency with Windows Server (2016, 2012, 2008) and working knowledge of Linux (Ubuntu, openSUSE and/or Red Hat).
• CCNA certification or similar networking certification.
• Experience with WordPress, or other CMS, HTML, CSS, and/or JS.
• Experience with Active Directory administration, deployments, and automation.
• Experience supporting remote employees or virtual organizations.
• Experience in Life Sciences Industry is recommended.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Associate/Senior Associate, Regulatory Affairs

Job #:02-255

Job Title: Associate/Senior Associate, Regulatory Affairs

Location: Waltham, Massachusetts

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking an Associate/Senior Associate, Regulatory Affairs to assist in the development and implementation of regulatory strategy for multiple projects and ensure execution of related regulatory submissions. Working in a team environment, the Associate/Senior Associate will be responsible for planning and coordinating multiple aspects of regulatory submissions necessary to support clinical trials and product registration.

This position will report to the Senior Manager, Regulatory Affairs and be located in the Waltham, MA office.

Key Responsibilities:
• Under supervision, the (Sr) Regulatory Affairs Associate will work with cross functional colleagues in providing support for regulatory filings, creation of internal regulatory documents, and assist with ensuring internal compliance with GXP regulations and policies
• Define contributions for submissions, communicate to functional contributors and track delivery according to agreed timelines
• Identifiy and compile all materials required in U.S. and/or ex-US regulatory submissions, this includes annual reports, DSURs for INDs, CTAs, IND/NDA/MAA applications, etc. as necessary
• Assist in coordination and compilation of responses to inquiries from global regulatory authorities
• Review regulatory submissions to ensure that the elements, quality, accuracy, and format are consistent and comply with applicable laws, regulations and corporate standards
• Develop and maintain current regulatory knowledge and keep abreast of regulatory procedures and changes
• Proficient in MS Office Applications including MS Outlook, MS Word, MS Excel, MS Powerpoint.

Required Qualifications:
• The Regulatory Affairs Associate is ideal for candidates with a BA/BS degree or higher with at least 2 years of professional experience in clinical research, regulatory affairs, or a related field regulated by the FDA. Title will be commensurate with education and experience.
• Proficiency in regulatory (FDA, ICH, GCP, and GMP) guidelines
• Keen planning skills but must also possess the skills to work in a high-paced work environment and be able to effectively manage multiple tasks
• Should be able to present their ideas clearly and concisely and have excellent written and oral communication skills
• Highly detail-oriented and organized
• Ability to positively interact with individuals from many departments
• Must have a working knowledge of Microsoft Office programs and Electronic Document Management Systems

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Manager, Quality Assurance Systems

Job #:02-254

Job Title: Manager, Quality Assurance (QA) Systems

Location: Waltham, Massachusetts

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:
• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking a Manager, Quality Systems who is will be responsible for developing, maintaining and executing Quality Management Systems (QMS) and processes to ensure GxP compliance. We are looking for a hands-on manager that can partner with internal departments to develop and support QMS process improvement implementations that meet business and regulatory requirements.

This position will report to the Associate Director, Quality Assurance, GCP and be located in the Waltham, MA office.

Key Responsibilities:
• Supports the Document Management Systems and assists in the system implementation, administration, migration and training of modules of Veeva Vault (QualityDocs, RIMS, QMS, eTMF, contracts management, platforms, etc.).
• Leads the implementation and administration of Quality Management Systems using the Veeva Vault modules for CAPA, Change Control, Deviations/Investigations and Vendor Management.
• Quality representative for the implementation of platform for the public disclosure module in Veeva Vault.
• Establish and implement effective QMS measurement, analysis, trending and reporting standards and processes.
• Assists with User Acceptance Testing, as well as oversee and participate, as needed, in validation.
• Establish and maintains the lifecycle of controlled documents, including but not limited to: records management including version control, periodic review, document distribution, archival, retrieval, retention and destruction.
• Act as the QA lead in identifying requirements, supporting validation testing verification and administration of all modules of Veeva Vault.
• Manage the training program, documentation of SOP read and understood training in QualityDocs.
• Manage the SafetySkills training program and provide quality metrics on compliance.
• Assist with the development and implementation of SOPs, training materials, system job aids, work instructions and help guide(s).
• Primary QA contact for Veeva Vault, SafetySkills and Starting Point (templates).
• Establish partnership and collaborate with Veeva IT administrator at Deciphera
• Primary point of contact with Veeva Administrators and Managed Services

Required Qualifications:
• Bachelor’s degree in Computer Science or related field.
• 5+ years IT experience in the life sciences industry
• Experience in Quality Assurance, process improvement or related function.
• Thorough knowledge of Quality Management Systems, and Quality Documentation Systems
• Strong software proficiency with Microsoft Suite, all modules of Veeva Vault, Starting Point, SafetySkills and other desktop applications
• Excellent communication, and collaboration skills

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Senior Accounts Payable Coordinator

Job #:: 03-213

Job Title: Senior Accounts Payable (A/P) Coordinator

Location: Waltham, Massachusetts

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking a Senior Accounts Payable (A/P) Coordinator to support all aspects of the accounts payable cycle.

This position will report to the Accounts Payable Specialist and be located in the Waltham, MA office.

Key Responsibilities:
• Prioritize, manage and process A/P entries for daily, weekly, monthly functions
• Review and audit expense reports for processing, adhering to company travel policy
• Input expense payable requests for reimbursement
• Process purchase orders into AP system upon complete review of approved and signed contract and audit of account coding
• Monitor the Accounts Payable inbox in Outlook and resolve invoicing requirements
• Obtain proper approvals for PO, invoices and payments
• Resolve invoice and payment disputes, including communication with vendors, as needed
• Distribute payments to include check, wires, ACH/credit card processing
• Maintain and reconcile vendor records and accounts
• Process 1099’s
• Assist team with GL and bank reconciliation, as needed
• Work with Accounting team on other accounting related projects

Required Qualifications:
• Bachelor’s Degree and 2+ years’ experience in accounts payable preferably in a biotech
• Working knowledge of Microsoft Office Suite (Outlook, Word and Excel)
• Experience with NetSuite and Concur, a plus
• Requires attention to detail and compliance with strict deadlines
• Strong organizational skills and ability to prioritize and multi-task
• Ability to effectively communicate, both verbally and in writing
• Experience working in a fast-paced, high-growth environment

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Manager/Senior Manager, GMP Quality Assurance (DS & P & L)

Job Title: Manager/Sr. Manager, GMP QA (Drug Substance & Packaging & Labeling)

Job #:02-253

Location: Waltham, MA

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients by tackling key mechanisms of drug resistance that limit the rate and/or durability of response to existing cancer therapies. Our small molecule drug candidates are directed against an important family of enzymes called kinases, known to be directly involved in the growth and spread of many cancers. We use our deep understanding of kinase biology together with a proprietary chemistry library to purposefully design compounds that maintain kinases in a “switched off’ or inactivated conformation. These therapies comprise tumor-targeted agents designed to address therapeutic resistance causing mutations and immuno-targeted agents designed to control the activation of immunokinases that suppress critical immune system regulators, such as macrophages. We have used our platform to develop a diverse pipeline of tumor-targeted and immuno-targeted drug candidates designed to improve outcomes for patients with cancer by improving the quality, rate and/or durability of their response to treatment. We offer an outstanding culture focused on:
• Providing a collaborative and energized work environment
• A diverse and multi-disciplinary workforce
• Dedicated and talented people who are passionate about achieving excellence in all they do
• A commitment to the patients we serve

We are seeking a Manager/Sr. Manager GMP/GDP Quality Assurance (DS & P & L) to provide expertise for the development and commercialization of Deciphera’s products in compliance with relevant US, EU and ICH requirements. The primary responsibility of this position will be to ensure proper QA oversight and collaboration with Deciphera’s Drug Substance (DS) and Packaging & Labeling (P&L) partners.
This position will report to the Director, GMDP & GLP Quality and be located in the Waltham, MA office.

Key Responsibilities:
• Assure compliance (internally and externally) with 21 CFR 210/211, 312, EudraLex Vol. 4 (including relevant parts and annexes) and ICH.
• Provide GMP oversight and management of daily quality related tasks and priorities of the clinical and commercial DS and P&L partners.
• Review and Approve Master Batch Production & Packaging Records and Executed Batch Production & Packaging Records.
• Responsible for all DS and P&L material disposition.
• Internal Quality lead for DS and P&L partner change controls, deviations, and investigations.
• Collaborate and support with internal stakeholders, along with DS and P&L partners on validation and technology transfer activities.
• Establish and maintain strategic business partnerships to ensure corporate deliverables are met.
• Create organizational procedures and processes for clinical and commercial programs.
• Develop, review and approve relevant Technical Quality Agreements.
• Assist in internal audit program and regulatory inspections.
• Support QP release activities.
• Review pertinent CMC sections of regulatory submissions.

Required Qualifications:
• B.S. degree in life sciences, chemistry or equivalent.
• 5+ years of GMP Quality experience, with at least 3 years managing external partners.
• Ability to manage multiple projects in a dynamic environment.
• Experience working with drug substance and packaging partners.
• A well organized, self-motivated and independent work style with the ability to initiate and follow through on expected duties.
• Excellent interpersonal skill with knowledge of basic negotiation, influencing and conflict management to assure effective interactions within and across departments.
• A strong team player is required with the ability to effectively communicate sound Quality advice cross-functionally based on experience, regulations and business needs.
• Proven track-record of leadership and building relationships with internal and external partners.
• Experience with using risk-based principles and decision making to ensure compliance at all stages of development.
• Ability to travel ~15% domestically and internationally.
• Must be authorized to work in the US.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Manager/Senior Manager, GMP Quality Assurance (DP)

Job #:02-252

Job Title: Manager/Sr. Manager, GMP QA (Drug Product)

Location: Waltham, MA

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients by tackling key mechanisms of drug resistance that limit the rate and/or durability of response to existing cancer therapies. Our small molecule drug candidates are directed against an important family of enzymes called kinases, known to be directly involved in the growth and spread of many cancers. We use our deep understanding of kinase biology together with a proprietary chemistry library to purposefully design compounds that maintain kinases in a “switched off’ or inactivated conformation. These therapies comprise tumor-targeted agents designed to address therapeutic resistance causing mutations and immuno-targeted agents designed to control the activation of immunokinases that suppress critical immune system regulators, such as macrophages. We have used our platform to develop a diverse pipeline of tumor-targeted and immuno-targeted drug candidates designed to improve outcomes for patients with cancer by improving the quality, rate and/or durability of their response to treatment. We offer an outstanding culture focused on:
• Providing a collaborative and energized work environment
• A diverse and multi-disciplinary workforce
• Dedicated and talented people who are passionate about achieving excellence in all they do
• A commitment to the patients we serve

We are seeking a Manager/Sr. Manager GMP/GDP QA (DP) to provide expertise for the development and commercialization of Deciphera’s products in compliance with relevant US, EU and ICH requirements. The primary responsibility of this position will be to ensure proper QA oversight and collaboration with Deciphera’s Drug Product (DP) partners.
This position will report to the Director, GMDP & GLP Quality and be located in the Waltham, MA office.

Key Responsibilities:
• Assure compliance (internally and externally) with 21 CFR 210/211, 312, EudraLex Vol. 4 (including relevant parts and annexes) and ICH.
• Provide GMP oversight and management of daily quality related tasks and priorities of the clinical and commercial DP partners.
• Review and Approve Master Batch Production Records and Executed Batch Production Records.
• Responsible for all DP material disposition.
• Internal Quality lead for DP partner change controls, deviations, and investigations.
• Collaborate with and support internal stakeholders, along with DP partners on validation and technology transfer activities.
• Establish and maintain strategic business partnerships to ensure corporate deliverables are met.
• Create organizational procedures and processes for clinical and commercial programs.
• Develop, review and approve relevant Technical Quality Agreements.
• Assist in internal audit program and regulatory inspections.
• Support QP release activities.
• Review pertinent CMC sections of regulatory submissions.

Required Qualifications:
• B.S. degree in life sciences, chemistry or equivalent.
• 5+ years of GMP Quality experience, with at least 3 years managing external partners.
• Experience working with small molecule drug products.
• Ability to manage multiple projects in a dynamic environment.
• A well organized, self-motivated and independent work style with the ability to initiate and follow through on expected duties.
• Excellent interpersonal skill with knowledge of basic negotiation, influencing and conflict management to assure effective interactions within and across departments.
• A strong team player is required with the ability to effectively communicate sound Quality advice cross-functionally based on experience, regulations and business needs.
• Proven track-record of leadership and building relationships with internal and external partners.
• Experience with using risk-based principles and decision making to ensure compliance at all stages of development.
• Ability to travel ~15% domestically and internationally.
• Must be authorized to work in the US.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Associate Director/Director, Analytical Development

Job #:04-210

Job Title: Associate Director/Director, Analytical Development

Location: Lawrence, Kansas

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:
• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking an Associate Director/ Director, Analytical Development to have overall responsibility for leading and managing early-stage CMC development activities related to analytical characterization of products/processes and the development, qualification, transfer and validation of analytical methods for QC release and stability testing of small-molecule drug substance, drug product, intermediates, starting materials, excipients, and packaging materials and components. Operating within a virtual (100% outsourced) business model, the incumbent will have accountability for analytical CRO/CDMO selection and oversight. The successful candidate will also assume a key leadership role in the development, review and approval of Module 3 sections of CTD regulatory submissions, written responses to regulatory authorities, and TPP/QTPPs.

This position will report to the Vice President, Chemical and Pharmaceutical Development and be located in the Lawrence, KS office.

Key Responsibilities:
• Working through CDMOs, Lead and manage analytical activities for GMP and non-GMP manufacture of drug substance and drug product, including method development/transfer, method validation, release testing, reference standard characterization, investigations for OOS.OOT results, etc.
• Oversee stability operations and reference standard management for early clinical assets.
• Develop and maintain strong relationships with CRO/CDMO business partners.
• Review/approve technical reports, controlled GMP documents (e.g., analytical methods and associated validation protocols, specifications, change controls, LIRs, SOPs, etc.) and incorporate CMC content for Module 3 CTDs.
• As needed, Represent the Technical Operations organization in meetings with FDA, EMA and related regulatory authorities.

Required Qualifications:
• A B.S./M.S. degree in analytical chemistry or related life sciences discipline with at least 10 years of experience in small-molecule pharmaceutical product development or commercialization (or) a PhD with 5 + years of relevant experience.
• Experience and in depth understanding of routine instrumental methods: HPLC, GC, Mass Spec
• Strong vendor/supplier management skills and excellent communication and cross-functional collaboration skills.
• Competency in developing, implementing and delivering CMC project plans (milestones, timelines, resources, etc.) to successful endpoints.
• Strong decision-making skills and ability to influence internal and external stakeholders.
• Thorough knowledge of the drug development process and ICH requirements for IND/IMPD filings. Track record of authoring and defending Module 3 CTD content.
• Ability to articulate complex issues and ideas with clarity to enable understanding and decision making.
• Ability to work successfully in a team/matrix environment and independently, as required.
• Ability to travel (10%) to CRO/CDMO domestic and international sites.

Preferred Qualifications:
• Prior experience leading and managing small-molecule analytical development in a 100% outsourced environment preferred.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Director, Drug Product Development

Job #::04-209

Job Title: Director, Drug Product Development

Location: Lawrence, Kansas

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:
• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking a Director, Drug Product Development to be responsible for the leadership and management of drug product development and manufacturing activities, including activities at contract research and manufacturing organizations, to support early phase clinical studies. Partnering with drug substance and analytical development teams, this individual will be responsible for the completion of IND-enabling development and drug product manufacturing for small molecule NCEs. The candidate will ensure timely manufacturing of drug product to support early clinical development programs. The Director will further contribute active support for regulatory CMC filings.

This position will report to the Vice President, Chemical and Pharmaceutical Development and be located in the Lawrence, KS office.

Key Responsibilities:
 Design and implement phase-appropriate drug product formulation development and supply strategies to support Deciphera’s pipeline and early clinical programs
 Serve as primary contact and manage CMOs/CROs in conduct of DP process development, process optimization, scale-up and clinical manufacturing.
 Work closely with chemical and analytical development functions
 Provide critical pre- and post-review of manufacturing batch records and integrate results into CMC regulatory filings
 Author and review regulatory reports/documents such as IND filings, IND updates, product development reports, quality summary, master batch records and other key reports/documents
 Potentially represent company in meetings with regulatory agencies
 Work with CMC senior leadership to create and communicate project strategy, plans and schedules that are aligned with company objectives and portfolio prioritization

Required Qualifications:
 Advanced degree (PhD preferred) in scientific or engineering discipline and 10 years of hands-on experience in pharmaceutical industry with drug product development for small molecules
 Experience in solid oral dosage forms.
 Clear written and verbal communication skills. Must be able to communicate effectively with executive leadership, consultants and contract research/manufacturing organizations
 Ability to direct and guide the work of CMOs.
 Understanding of cGMP manufacturing
 Strong project management experience
 Experience in process scale-up and transfer
 Demonstrated ability to multi-task under pressure and ability to prioritize competing activities
 Prior authorship of INDs, IMPDs
 Late stage development and commercialization experience is a plus

Preferred Qualifications:
 Familiarity with US and international regulatory CMC guidance and processes
 Prior experience filing NDAs highly desirable
 Excellent computer skills (e.g., Microsoft Office, Excel, Project)
 Strong organizational skills with attention to detail and ability to manage multiple projects at once
 Ability to work both independently and in a team focused environment
 Ability to travel up to 15% to support CDMO relationships/manufacturing

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Manager/Senior Manager, Clinical Quality Assurance

Job #:02-251

Job Title: Manager/Senior Manager, Clinical Quality Assurance

Location: Waltham, Massachusetts

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking a Manager/Senior Manager, Clinical Quality Assurance to be responsible for the development, maintenance and oversight of GCP activities related to the Clinical Trial activities sponsored by Deciphera. The primary responsibilities will be to ensure that both quality and compliance of Deciphera sponsored clinical trials with respect to Standard Operating Procedures, applicable regulatory requirements (US FDA, ICH, and country specific), along with current industry standards and practices.

This position will report to the Associate Director, Quality Assurance and be located in the Waltham, MA office.

Key Responsibilities:
• Draft, review or revise Clinical SOPs to assess consistency and compliance with regulatory requirements/internal standards
• Attend cross-functional team meetings and provide guidance to clinical operations staff based on interpretation of current regulations to ensure best practices including risk-based management
• Work closely with Clinical Operations to ensure/coordinate appropriate and complete resolution of findings/non-compliant issues, quality investigations, etc. in a timely manner, including approval of corrective action and preventative action (CAPA) plans, as necessary
• Conduct and/or assist in internal audits (systems, processes, vendors, computer system validation)
• Work directly with CRO’s and other external contractors and collaborators, managing the chain of communication related to GCP compliance
• Interact with contract auditors in the scheduling process, kick-off meetings with auditors and internal groups, assist in the drafting of audit plans, confirmation letters and agendas, etc.
• Identify the need for, conduct and/or assist in external audits (includes, but is not limited to, investigator sites, central IRBs, CROs and clinical labs)
• Oversee the audit response process for the Investigator Site and Contract Research Organization (CRO) audits/inspections and ensure acceptability of actions to address findings through the CAPA process
• Provide Quality Control (QC) review of clinical protocols, amendments, Informed Consent Forms, Clinical Study Reports and other clinical trial related documents
• Assist and advise with training QA and clinical staff as necessary for GCP
• Identify potential systemic gaps and coordinate with the appropriate stakeholder to ensure timely remediation
• As appropriate, escalate issues of critical non-compliance and/or lack of urgency in remediation to senior management via the Quality Board
• Perform program specific root cause analysis of compliance issues and provide the appropriate metrics for tracking and trending for the overall QA reporting requirements to functional and senior management
• Assist with inspection readiness, and regulatory inspections as needed

Required Qualifications:
• At least 5 years of direct GCP pharmaceutical/biotechnology experience
• Solid understanding and application of GCP, GLP and ICH requirements, especially ICH E6R2
• A well organized, self-motivated and independent work style with the ability to initiate and follow through on assignments
• Excellent interpersonal skills with knowledge of basic negotiation, influencing and conflict management to assure effective interactions within and across departments
• The ability to simultaneously handle multiple project issues while dealing with time demands, incomplete information, or unexpected events
• Ideal candidate will have broad experience in product development, clinical operations, regulatory compliance and GCP auditing
• A strong team player is required with the ability to effectively communicate sound Quality advice cross-functionally based on experience, regulations & business needs
• Experience with using risk-based principles & decision making to ensure compliance at all stages of development
• Proven track-record of leadership & building relationships with both internal & external customers
• Strong negotiation skills, flexibility & ability to provide a solution-based approach to emerging challenges

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Associate Director/Director, Clinical Scientist

Job #:02-250

Job Title: Associate Director/Director, Clinical Scientist

Location: Waltham, Massachusetts

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
This position may be filled at Associate Director or Director level based on candidate’s skills/experience and will report to the Sr Director, Clinical Research at Deciphera’s corporate headquarters in Waltham, MA.

Key Responsibilities:
• Works closely with Medical Directors, Pharmacology, Discovery, external experts, and investigators to accumulate scientific and medical knowledge necessary to support clinical development plans and study designs and protocols
• Assists Medical Directors in creation of proposed concept sheets for clinical studies and may write protocols or work with medical writing to write protocols through incorporation of input from both internal and external experts
• Drives the clinical contribution to annual update of IB liaising with Toxicology, Pharmacology, Safety, Regulatory and Medical & Communication Experts
• Drives and integrates clinical contribution to answering regulatory queries and other submissions related to studies
• Monitors real time study data to ensure the integrity of the study and the study data and interacts with investigators and internal and external experts to resolve any study issues as they arise
• Involved in high level data cleaning activities requiring clinical judgment Involved in analysis of complex data for regulatory submissions, publications and design of studies and programs
• Acts as clinical/scientific expert on the products and studies in the therapy area
• Attends scientific meetings to remain abreast of new developments within relevant areas and to interact with investigators, and advisors
• Works with investigative sites to answer protocol related questions, resolve study conduct and design issues
• May present data, protocol designs and other information at advisory boards, investigator meetings, site initiations and other internal and external settings

Required Qualifications:
• MS in Life Sciences (or BS plus equivalent experience); Pharm D, or BSN or other equivalent clinical qualifications
• 8 years’ experience in product & clinical development (Clinical Scientist role) in Biotech or Pharmaceutical company
• Understanding of GCP, ICH and regional/local regulations
• Experience in both early and late phase development
• Medical knowledge and experience in clinical development/ operations (Oncology preferred)
• Experience reviewing clinical data outputs
• Ability to perform literature searches and to utilize library services
• Ability to conduct basic data analyses using Excel and other tools
• Basic understanding of biostatistics to allow effective interaction with biostatistics expert
• Requires approximately 15-30% travel

Preferred Qualifications:
• Teaching capability
• Excellent communication skills, both verbal and in writing
• Strong presentation skills
• Team player
• Ability to proactively predict issues and solve problems
• Ability to drive decision-making within a multi-disciplinary, multi-regional matrix team
• Diplomacy and positive influencing abilities
• Experience building data presentation plans

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Associate Director, SAS Programmer

Job #::02-249

Job Title: Associate Director, SAS Programming

Location: Waltham, Massachusetts

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

Position Summary:
We are seeking an Associate Director, SAS Programming to join our biometrics group.
This position will report to the Senior Director, Head of Biometrics and be located in the Waltham, MA office.

Key Responsibilities:
• Serves as a lead programmer for a compound or key NDA related activities
• Efficiently manage CROs to meet timelines and expectation of quality
• Works collaboratively with other functions to ensure clarity, accuracy and consistency of case report forms (CRFs), develop and comply with project/study programming standards and specifications according to regulatory guidelines
• Programs for SDTM data mapping and creation of ADaM datasets and the corresponding specifications according to CDISC standards
• Programs TLFs for implementation of the statistical analysis plans and for AdHoc analysis in clinical trial of all phases
• Performs programming QC on TLFs
• Tracks clinical trial milestones and works with vendors for statistical reporting deliverables.
• Maintains records for all assigned projects and archiving of trial/project analysis and associated documentation
• Understands and performs in accordance with regulatory standards, and drug development principles
• Responsible for the creation and accuracy of Regulatory submission data and clinical summary report package
• Plans, develops, tests, and documents SAS macros for programming efficiency

Required Qualifications
• 8+ years in statistical programming within the Pharmaceutical industry
• Strong understanding of clinical trial processes and statistical programming requirements for regulatory submissions
• Excellent SAS Software Programming skills, including Base SAS, SAS/STAT, SAS/GRAPH and macro development
• Ability to define and implement CDISC compliant SDTM and ADaM data and specifications
• Oncology experience is a plus

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plans, life insurance and a flexible spending account for health care and/or dependent care.

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Principal/Associate Director, Statistician

Job #::02-247

Job Title: Principal/Associate Director, Statistician

Location: Waltham, Massachusetts

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

We are seeking a Principal/Associate Director, Statistician to join the Biostatistics Group.
This position will report to the Senior Director, Biometrics and be located in the Waltham, MA office.

Key Responsibilities:
• Serve as a lead statistician and manage statistical efforts for multiple clinical studies and/or a clinical program
• Contribute to clinical protocol development, including authoring of the section on statistical methods and reviewing/editing of other sections by applying statistical principles
• Author statistical analysis plans for studies and/or ISS/ISEs, and author/edit shells for tables, figures and listings
• Review CRF designs to ensure data collection meet the study objectives and the requirements of statistical analyses
• Provide statistical input to data monitoring committee (DMC) charters, project management plan, and other study-level documents
• Work with statistical programmers or CROs to generate tables, figures and listings
• Perform ad hoc and exploratory statistical analyses as needed
• Contribute to clinical study reports, including authoring of statistical sections and interpretation of the study results
• Support regulatory submissions as needed; provide response to regulatory requests independently
• Support the preparation of publications, including manuscripts, posters and oral presentations
• Provide oversight of CROs for outsourced statistical activities and QC key results generated by CROs

Required Qualifications:
• Principal Statistician: PhD in statistics or a related field with at least 4 years of relevant clinical trial experience or MS in statistics or equivalent with at least 6 years of relevant clinical trial experience
• Associate Director, Statistician: PhD in statistics or a related field with at least 6 years of relevant clinical trial experience or MS in statistics or equivalent with at least 8 years of relevant clinical trial experience
• Knowledge of statistical methods for clinical trials
• In-depth Knowledge of FDA, EMA and ICH regulations and guidelines
• Proficient in statistical programming (SAS is required)
• Experience with trial design software (e.g., EAST or nQuery)
• Good communication skills and ability to work with cross-functional study teams
• Good organizational skills, sufficient to multi-task in an extremely fast-paced environment with changing priorities
• Good analytical and problem-solving skills
• Positive and collaborative attitude

Preferred Qualifications:
• Experience with NDAs/BLAs, MAAs and other regulatory submissions is a plus
• Proficient in running simulations using either SAS or R

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Senior Clinical Data Manager

Job #::02-246

Job Title: Senior Clinical Data Manager

Location: Waltham, MA

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

We are seeking a seasoned Clinical Data Manager who can lead and contribute to data management activities in support of Deciphera studies across all stages of clinical drug development. This position will report to the Associate Director of Data Management and will be located in the Waltham, MA office.

Key Responsibilities:
• Contribute to data management activities as a lead study data manager in support of Deciphera clinical studies
• Participate in the development of all Data Management documentation including the Data Management Plan, CRF Completion Guidelines, Data Validation Specification, E-Data Reconciliation Plans, Data Review Plan, etc.
• Perform clinical data processing/management including query generation, electronic data reconciliation etc.
• Plans and oversees execution of User Acceptance Testing
• Assist in preparing clean databases, including reviewing responses to queries for appropriateness, resolve any discrepancies and modifying the database accordingly
• Ensures study compliance with SOPs and regulations
• Identify and troubleshoot operational problems, issues, obstacles and barriers for studies based on metrics data, audit reports, and input from project team members and other stakeholders
• Ability to communicate well and represent data management effectively and diplomatically in a project team environment
• Liaise with CRO’s, EDC vendors and other third-party vendors
• Monitor timelines and ensures that clinical data management deadlines are met with quality
• Support GCP inspection readiness
• Performs other duties as assigned

Required Qualifications:
• Prefer B.S. (or equivalent degree) in a scientific or allied health field and 4-6 years of relevant work experience in the Pharmaceutical Industry or CRO
• Demonstrated experience with Electronic Data Capture (EDC)
• Knowledge of clinical research, medical terminology/disease processes and clinical practice
• Strong interpersonal, communication, organization, critical thinking, and problem-solving skills; able to adapt to internal/external deadlines and oversee vendors
• Experience working with MSOffice Suite (Excel, Word, PowerPoint)

Preferred Qualifications:
• Experience with the implementation of industry standards (CDISC, CDASH, and SDTM)
• Overall understanding of ICH, GCP, CDISC and other applicable regulatory guidelines as they pertain to data management
• Highly motivated; detail and process oriented; welcomes challenge and responsibility; team-player and can achieve results in a fast paced and changing environment

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Manager/Senior Manager, Strategic Clinical Outsourcing

Job #:02-244

Job Title: Manager/Senior Manager, Strategic Clinical Outsourcing

Location: Waltham, Massachusetts

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:
• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

We are seeking a Manager/Senior Manager, Strategic Clinical Outsourcing to support all clinical outsourcing activities as well as other corporate sourcing activities as requested. The position will work cross-functionally with internal stakeholders such as Data Management, Biostatistics, Translational Medicine, Legal, and Finance. General responsibilities include working with teams to properly assess outsourcing opportunities and provide contractual negotiation support, performance monitoring and follow-up. The successful candidate must be hands-on and comfortable developing procedures, templates, and relationships and work with the Director to contribute to growth and future state of the organization.

This position will report to the Director, Strategic Outsourcing and be located in the Waltham, MA office.

Key Responsibilities:
• Support the outsourcing process and activities for Clinical Development.
• Manage contracting activities including the preparation, finalization, and administration of CDAs, MSAs, Service Agreements, Work Orders, Change Orders, and Amendments while minimizing risk across a broad scope of clinical / therapeutic outsourcing services.
• Assist and/or manage the identification and selection process of clinical vendors such as CROs, central labs, IRT, Imaging, ePRO, Safety vendors, etc.
• Work closely with Clinical Business Operations and Finance to assure the assumptions for studies are aligned between finance and clinical forecasting.
• Meet with clinical trial managers, functional managers, Legal, and QA as needed to ensure vendors are meeting expectations and review progress against contract.
• Create and maintain outsourcing/vendor oversight standards and templates.
• Contribute to the development of an established preferred clinical vendor list.

Required Qualifications:
• Bachelor’s degree with at least five to eight years of experience with a focus on developing and overseeing clinical budgets, and contracts with clinical outsourcing vendors in the pharmaceutical/biotech industry (an equivalent combination of experience and education may be considered)
• At least four years of direct clinical trial and/or vendor oversight experience required; experience negotiating, administering, extending, terminating, and re-negotiating contracts
• Excellent interpersonal, organizational and multi-tasking skills.
• Ability to interface with vendors, collaborators, all internal departments and all levels of management
• Understanding of Clinical/Drug Development; familiar with Regulatory Guidelines including ICH GCP.
• Previous experience working with clinical operations and finance is preferred.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Senior Operations Specialist, Translational Medicine

Job #: 02-245

Job Title: Senior Operations Specialist, Translational Medicine

Location: Waltham, Massachusetts

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients. We have used our proprietary drug discovery platform to develop a diverse pipeline of drug candidates designed to improve outcomes for patients with cancer by enhancing the quality, rate and/or durability of their responses to treatment. We currently retain global development and commercialization rights to our drug candidates, including three programs in clinical development. Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered just outside Boston in Waltham, Massachusetts. Our state-of-the-art research facility is located near the University of Kansas School of Pharmacy in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:

• providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
• a diverse and multi-disciplinary workforce
• dedicated and talented people who are passionate about achieving excellence in all they do
• a work environment that allows you to balance your priorities
• above all else, a commitment to the patients we serve

We are seeking a Translational Medicine Operations Specialist to work across all programs, partnering primarily with colleagues in Clinical Development, Clinical Operations and Program Management to ensure robust clinical sample and vendor management is in compliance with protocols, regulatory guidance and project timelines. The TM Operation Specialist will be responsible and accountable for managing/overseeing the entire sample and vendor management process for assigned projects from acquisition through analysis and final disposition.

This position will report to the Head of Translational Medicine and be located in the Waltham, MA office.

Key Responsibilities:
• Work closely with Clinical Operations and Translational Medicine to coordinate and manage the sample collection for on-going and planned clinical trials that have translational medicine objectives in their design.
• Manage kit preparation, sample collection procedures, shipping requirements, analytical data collection/reporting.
• Ensure robust chain-of-custody for clinical trial specimens.
• Manage contracts (material transfer agreements) with academic institutions and/or commercial partners that provide bio-specimens as part of collaborative or service provider agreements.
• Ensure/verify that collaborators have appropriate documentation, process and procedures in place to ensure samples are collected according to ethical and legal standards (both prospective or retrospective sampling)
• Manage budget negotiations
• Provide clinical trial budget forecasts that relate to all aspects of sample management (acquisition, transport, storage, analysis)
• Develop knowledge/understanding of regional bio-specimen applicable regulations to help facilitate protocol approvals by global ethics committees.

Required Qualifications:
• BS or MS degree in science with a strong track record in bio-pharma industry working on clinical development projects and in cross-functional team environment
• 3-5+ years of experience in industry
• Must have CRO/Vendor management experience
• Experience with contract and budget development, negotiation, and management; vendor management; and data and sample management
• Knowledge of GCPs for global compliance
• Protocol development experience a plus
• Interpersonal skills required to communicate effectively with collaborators and cross functional teams.
• Highly motivated and enjoys working in a fast-paced, dynamic environment.
• Excellent writing skills.
• Strong project management skills.
• Strong organizational skills, ability to prioritize and handle competing priorities.
• Positive, flexible self-starter who thrives under pressure.
• Excellent judgement and problem-solving skills.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Associate Director/Director, Medical Writing

Job #: – 02-236

Job Title: Associate Director/Director, Medical Writing

Location: Waltham, MA

Role Summary:
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients by tackling key mechanisms of drug resistance that limit the rate and/or durability of response to existing cancer therapies. Our small molecule drug candidates are directed against an important family of enzymes called kinases, known to be directly involved in the growth and spread of many cancers. We use our deep understanding of kinase biology together with a proprietary chemistry library to purposefully design compounds that maintain kinases in a “switched off’ or inactivated conformation. These therapies comprise tumor-targeted agents designed to address therapeutic resistance causing mutations and immuno-targeted agents designed to control the activation of immunokinases that suppress critical immune system regulators, such as macrophages. We have used our platform to develop a diverse pipeline of tumor-targeted and immuno-targeted drug candidates designed to improve outcomes for patients with cancer by improving the quality, rate and/or durability of their response to treatment.

We are seeking an Associate Director/Director, Medical Writing to be responsible for providing Medical Writing leadership for late stage clinical and regulatory affairs activities.

This position will report to the Vice President Regulatory Affairs & Quality Assurance and be located in the Waltham, MA office.

Key Responsibilities:
• Coordinate document development strategies with various functional areas in Clinical Development and Regulatory Affairs to produce high quality work that is compliant with GCP and ICH guidelines
• Act as Lead Medical Writer
• Represent Medical Writing on cross-functional clinical and regulatory teams and actively participate in NDA submission planning and documentation
• Plan and coordinate work with in-house Medical Writers and outside CROs to ensure quality deliverables within assigned time frames

Required Qualifications:
• Experience in development of clinical documents related to late phase studies.
• NDA experience with active contribution in planning and preparation of summary documents is required
• Bachelor’s Degree; Advanced degree (MS or Ph.D.) in a relevant scientific field preferred
• 10+ years of industry experience as a Medical Writer with experience working in a small biopharmaceutical company

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Associate Director, Quality Control

Job #: 02-231

Job Title:  Associate Director, Quality Control

Location:  Waltham, MA

Role Summary:

Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients by tackling key mechanisms of drug resistance that limit the rate and/or durability of response to existing cancer therapies. Our small molecule drug candidates are directed against an important family of enzymes called kinases, known to be directly involved in the growth and spread of many cancers. We use our deep understanding of kinase biology together with a proprietary chemistry library to purposefully design compounds that maintain kinases in a “switched off’ or inactivated conformation. These therapies comprise tumor-targeted agents designed to address therapeutic resistance causing mutations and immuno-targeted agents designed to control the activation of immunokinases that suppress critical immune system regulators, such as macrophages. We have used our platform to develop a diverse pipeline of tumor-targeted and immuno-targeted drug candidates designed to improve outcomes for patients with cancer by improving the quality, rate and/or durability of their response to treatment.

We are seeking an Associate Director, Quality Control, who will have responsibility for leading and managing the pharmaceutical GMP quality control activities associated with development and commercialization of the company’s small-molecule assets. Operating within a virtual (100% outsourced) business model, the incumbent will be responsible for site implementation of IPC and QC methods for drug substance, drug product, intermediates, starting materials, excipients, and packaging materials and components, review/approval of protocols, methods, reports, batch records and related GMP source documents, oversight of stability operations and reference standard management, and transfer/site implementation of analytical methods to support future supply chain expansion.

The successful candidate will also work collaboratively with Quality Assurance to assess laboratory conformance with cGMPs, and with CMC Regulatory Affairs to ensure the translational accuracy and integrity of data incorporated into Module 3 sections of CTD regulatory submissions and written responses to regulatory authorities.

This position will report to the Senior Director, Analytical Development and MS&T and be located in the Waltham, MA office.

Key Responsibilities:

  • Manage/oversee qualification and site implementation of IPC and QC methods for drug substance, drug product, intermediates, starting materials, excipients, and packaging materials and components.
  • Manage/oversee analytical method transfers and site implementation to support supply chain expansion activities and post-approval continuous improvement initiatives.
  • Manage/oversee stability operations and reference standard program.
  • Participate in the selection of analytical CROs/CDMOs based upon core capabilities and regulatory compliance.
  • Review/approve controlled GMP documents, e.g., analytical methods and associated validation protocols, specifications, change controls, LIRs, etc.
  • Review/approve development reports for data integrity and regulatory compliance; review/approve CMC content incorporated into Module 3 sections of CTD regulatory submissions for translational accuracy.
  • Support cGMP audits of CDMO laboratories.
  • Author and/or review standard operating procedures (SOPs) relating to analytical development and quality control.
  • Maintain effective communication with CDMOs and deliver QC objectives in accordance with project timelines and budgets.

Required Qualifications:

  • S./M.S. degree in analytical chemistry or related life sciences discipline with at least 10 years of quality control experience in pharmaceutical product development.
  • In-depth understanding of CMC regulatory requirements for product registration and cGMP compliance requirements for pharmaceutical quality control laboratories.
  • Strong vendor/supplier management and cross-functional collaboration skills.
  • Ability to work successfully in a team/matrix environment and independently, as required.
  • Ability to meet deadlines, demonstrate efficient and effective use of time, and handle multiple assignments simultaneously.
  • Ability to convey both written and verbal information effectively and efficiently.
  • Ability to follow procedures and perform assignments with a high degree of accuracy and careful attention to detail.
  • Ability to travel (15%) to CRO/CDMO domestic and international sites.

 Preferred Qualifications:

  • Experience in developing and commercializing drugs for oncology and/or orphan diseases is desirable.
  • Significant work experience in a virtual (100% outsourced) biopharmaceutical development business model is strongly preferred.

 

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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