Vimseltinib for Patients With Tenosynovial Giant Cell Tumor: A Multicenter, Open-Label, Phase 2 Trial

Stacchiotti S, et al. Cancer. 2026;132(17):e70564.

This phase 2 study evaluated the safety and efficacy of vimseltinib in patients with tenosynovial giant cell tumor not amenable to surgery, including both patients with and without prior treatment with anti-CSF1/CSF1R therapies. Key outcomes included antitumor activity, active range of motion, patient-reported outcomes, and safety. 

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