Long-term efficacy, clinical outcomes, and safety of vimseltinib in patients with tenosynovial giant cell tumor: results from the MOTION phase 3 trial

Bhadri V, et al. The Oncologist. 2026;31(11):https://doi.org/10.1093/oncolo/oyag421.

This publication reports long-term results from the phase 3 MOTION study of vimseltinib in patients with tenosynovial giant cell tumor not amenable to surgery, with >2 years of followup on study. Key outcomes included antitumor activity, clinical outcome assessments, and safety. Results showed robust and durable antitumor activity and long-term improvements in clinical outcome assessments, with a safety profile consistent with prior reports.

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DCPH-M01358v1 11/2026