Drug Pipeline
Preventing disease-causing kinases from adopting aggressive shapes (conformations) and solving the problem of drug resistance provides patients with more durable kinase blocking therapies. These Deciphera candidates also exhibit high selectivity profiles, enabling the inhibition of specific disease-causing kinases without affecting the function of a host of other kinases required for normal health. This translates into safer therapies and extends the clinical use of kinase inhibitors into the area of chronic non-oncology indications.
To learn additional information, please select a drug candidate below.
Term ID: 3
Targeted kinases:
TIE-2, BCR-ABL
Targeted cancers:
breast, glioblastoma, metastatic melanoma, ovarian, renal, colon
Dose Form:
Term ID: 2
Targeted kinases:
B-RAF, C-RAF
Targeted cancers:
melanoma
Dose Form:
Targeted kinases:
cMET, TIE-2, VEGFR2
Targeted cancers:
solid tumors and highly invasive metastatic cancers
Dose Form:
Targeted kinases:
cMET
Targeted cancers:
solid tumors and highly invasive metastatic cancers
Dose Form:
Targeted kinases:
mutant cKIT (including exons 14 and 17) and mutant PDGFRα
Targeted cancers:
gastrointestinal stromal tumors (GIST), mast cell leukemia, mastocytosis
Dose Form:
Term ID: 1
Targeted kinases:
selective cFMS inhibitor
Targeted cancers:
gliomas, breast cancer, tumor metastases and bone metastases
Dose Form:
